3QR0

Crystal Structure of S. officinalis PLC21

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004435	molecular_function	phosphatidylinositol-4,5-bisphosphate phospholipase C activity
A	0006629	biological_process	lipid metabolic process
A	0007165	biological_process	signal transduction
A	0008081	molecular_function	phosphoric diester hydrolase activity
A	0035556	biological_process	intracellular signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 1000

Chain	Residue
A	ASN339
A	GLU368
A	ASP370
A	GLU417
A	HOH927
A	HOH1029

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 1200

Chain	Residue
A	VAL584
A	ILE587
A	ILE605
A	PHE804
A	ASP806
A	HOH819
A	ARG577
A	ASN582
A	TYR583

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1201

Chain	Residue
A	GLN258
A	TYR271
A	GLU310
A	ASN311
A	LYS742
A	ARG746
A	HOH917

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1202

Chain	Residue
A	GLU672
A	GLU674
A	ARG684
A	LYS685
A	ARG720
A	HOH882

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1203

Chain	Residue
A	LYS48
A	GLU156
A	HOH1078
A	GOL1205

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 1204

Chain	Residue
A	LYS59
A	HIS383
A	GLY384
A	PHE385
A	THR503
A	GLY575
A	HOH951
A	HOH1014

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1205

Chain	Residue
A	GLU156
A	PHE215
A	HOH1034
A	GOL1203

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1206

Chain	Residue
A	GLU497
A	LYS498
A	SER543
A	MET544
A	VAL545
A	GLN548
A	TYR572

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1207

Chain	Residue
A	TYR114
A	ILE115
A	SER352
A	ILE355
A	GLN358
A	HOH892

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1208

Chain	Residue
A	THR362
A	LEU611
A	GLU615
A	ASN755
A	ARG756

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