3QQM
Crystal structure of a Putative amino-acid aminotransferase (NP_104211.1) from Mesorhizobium loti at 2.30 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0046394 | biological_process | carboxylic acid biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0046394 | biological_process | carboxylic acid biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0019752 | biological_process | carboxylic acid metabolic process |
| C | 0046394 | biological_process | carboxylic acid biosynthetic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0019752 | biological_process | carboxylic acid metabolic process |
| D | 0046394 | biological_process | carboxylic acid biosynthetic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0019752 | biological_process | carboxylic acid metabolic process |
| E | 0046394 | biological_process | carboxylic acid biosynthetic process |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0019752 | biological_process | carboxylic acid metabolic process |
| F | 0046394 | biological_process | carboxylic acid biosynthetic process |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0019752 | biological_process | carboxylic acid metabolic process |
| G | 0046394 | biological_process | carboxylic acid biosynthetic process |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0019752 | biological_process | carboxylic acid metabolic process |
| H | 0046394 | biological_process | carboxylic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 221 |
| Chain | Residue |
| A | GLU90 |
| A | ARG212 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 225 |
| Chain | Residue |
| A | ARG31 |
| A | LEU214 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IOD A 234 |
| Chain | Residue |
| A | ILE153 |
| A | ASN209 |
| A | ARG212 |
| A | HOH1082 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 248 |
| Chain | Residue |
| A | GLN24 |
| A | ARG22 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 250 |
| Chain | Residue |
| A | LEU46 |
| A | ARG78 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 252 |
| Chain | Residue |
| A | ARG169 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 258 |
| Chain | Residue |
| A | ASP33 |
| A | HOH819 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 260 |
| Chain | Residue |
| A | GLU182 |
| A | GLU186 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 265 |
| Chain | Residue |
| A | GLU16 |
| A | ALA75 |
| A | ASP81 |
| A | THR83 |
| B | ASP61 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 270 |
| Chain | Residue |
| A | LEU113 |
| A | HIS116 |
| A | THR118 |
| A | ARG120 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 272 |
| Chain | Residue |
| A | ARG121 |
| A | THR125 |
| A | THR152 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 275 |
| Chain | Residue |
| A | ARG128 |
| A | ASP137 |
| A | GLU138 |
| A | THR152 |
| A | ILE153 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 279 |
| Chain | Residue |
| A | LEU92 |
| A | ALA93 |
| A | HOH511 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 303 |
| Chain | Residue |
| A | LEU205 |
| A | PHE206 |
| A | ALA217 |
| A | HOH1021 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 306 |
| Chain | Residue |
| A | LYS96 |
| A | VAL133 |
| A | ASP137 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 309 |
| Chain | Residue |
| A | ARG67 |
| A | THR68 |
| A | MSE70 |
| B | GLU90 |
| B | HOH969 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD B 236 |
| Chain | Residue |
| B | ILE153 |
| B | ARG212 |
| B | HOH1084 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 240 |
| Chain | Residue |
| B | LEU214 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD B 242 |
| Chain | Residue |
| B | ASP108 |
| B | ASN111 |
| B | LEU123 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 261 |
| Chain | Residue |
| B | PRO25 |
| B | GLY26 |
| B | ALA66 |
| C | THR112 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 280 |
| Chain | Residue |
| B | LEU113 |
| B | HIS116 |
| B | THR118 |
| B | ARG120 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 285 |
| Chain | Residue |
| B | ARG31 |
| B | ARG34 |
| B | GLU182 |
| B | HOH919 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 292 |
| Chain | Residue |
| B | TYR194 |
| B | ASP198 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 293 |
| Chain | Residue |
| B | ARG121 |
| B | THR125 |
| B | ARG128 |
| B | THR152 |
| B | HOH1001 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 294 |
| Chain | Residue |
| B | THR20 |
| B | LLP117 |
| B | ASN209 |
| B | HOH506 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 299 |
| Chain | Residue |
| B | ARG104 |
| B | GLU130 |
| B | TYR131 |
| F | ASP162 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD C 226 |
| Chain | Residue |
| C | ARG31 |
| C | LEU214 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD C 233 |
| Chain | Residue |
| C | ASP108 |
| C | ASN111 |
| C | LEU123 |
| site_id | DC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD C 239 |
| Chain | Residue |
| C | ILE153 |
| C | ARG212 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 269 |
| Chain | Residue |
| C | LEU113 |
| C | HIS116 |
| C | THR118 |
| C | ARG120 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 278 |
| Chain | Residue |
| C | ARG31 |
| C | ASP33 |
| C | ARG34 |
| C | GLU182 |
| C | HOH696 |
| site_id | DC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 286 |
| Chain | Residue |
| C | ILE193 |
| D | GLU144 |
| D | ARG145 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 295 |
| Chain | Residue |
| C | THR20 |
| C | LLP117 |
| C | ASN209 |
| C | HOH423 |
| C | HOH816 |
| site_id | DC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 302 |
| Chain | Residue |
| C | PHE160 |
| C | GLY161 |
| C | ASP162 |
| D | ARG106 |
| D | ASN143 |
| D | GLU144 |
| D | GLY146 |
| site_id | DC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 304 |
| Chain | Residue |
| C | ARG128 |
| C | ASP137 |
| C | GLU138 |
| C | THR152 |
| C | ILE153 |
| C | HOH796 |
| site_id | DC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 307 |
| Chain | Residue |
| C | LEU199 |
| C | LYS200 |
| C | ALA202 |
| C | LEU219 |
| site_id | EC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD D 222 |
| Chain | Residue |
| D | GLU90 |
| D | ARG212 |
| site_id | EC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD D 227 |
| Chain | Residue |
| D | ARG31 |
| D | LEU214 |
| site_id | EC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IOD D 232 |
| Chain | Residue |
| D | ILE153 |
| D | ASN209 |
| D | ARG212 |
| D | EDO290 |
| site_id | EC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL D 257 |
| Chain | Residue |
| D | ARG78 |
| site_id | EC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 259 |
| Chain | Residue |
| D | ARG31 |
| D | ASP33 |
| D | HOH908 |
| site_id | EC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 263 |
| Chain | Residue |
| C | VAL58 |
| C | ASP61 |
| D | GLU16 |
| D | ALA75 |
| D | ALA77 |
| D | ASP81 |
| D | THR83 |
| site_id | EC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 264 |
| Chain | Residue |
| D | LEU113 |
| D | HIS116 |
| D | THR118 |
| D | ARG120 |
| D | HOH886 |
| site_id | EC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 271 |
| Chain | Residue |
| C | ASP198 |
| D | ASN143 |
| D | ARG145 |
| D | GLU147 |
| D | ASP171 |
| D | ILE193 |
| site_id | EC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 277 |
| Chain | Residue |
| D | GLN24 |
| D | TYR89 |
| D | PRO91 |
| site_id | FC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 282 |
| Chain | Residue |
| D | ARG169 |
| D | GLU191 |
| D | HOH454 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 284 |
| Chain | Residue |
| D | ARG121 |
| D | THR125 |
| D | HOH467 |
| D | HOH634 |
| site_id | FC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 287 |
| Chain | Residue |
| D | ARG128 |
| D | ASP137 |
| D | GLU138 |
| D | THR152 |
| D | ILE153 |
| D | HOH467 |
| site_id | FC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 289 |
| Chain | Residue |
| D | ASN111 |
| D | LEU114 |
| D | ARG120 |
| D | ARG121 |
| D | GLN122 |
| D | LEU123 |
| D | HOH862 |
| D | HOH938 |
| site_id | FC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 290 |
| Chain | Residue |
| D | ARG212 |
| D | IOD232 |
| site_id | FC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 291 |
| Chain | Residue |
| D | LEU92 |
| D | ALA93 |
| D | HOH746 |
| site_id | FC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 296 |
| Chain | Residue |
| D | ALA56 |
| E | PRO52 |
| E | GLN53 |
| site_id | FC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 310 |
| Chain | Residue |
| D | LEU205 |
| D | PHE206 |
| D | ALA217 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD E 231 |
| Chain | Residue |
| E | ARG71 |
| E | ILE153 |
| E | ARG212 |
| site_id | GC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD E 241 |
| Chain | Residue |
| E | HOH449 |
| site_id | GC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL E 247 |
| Chain | Residue |
| E | ARG31 |
| site_id | GC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL E 251 |
| Chain | Residue |
| E | ARG78 |
| site_id | GC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL E 256 |
| Chain | Residue |
| E | ASP108 |
| E | ASN111 |
| E | LEU123 |
| E | EDO273 |
| site_id | GC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO E 266 |
| Chain | Residue |
| E | LEU113 |
| E | HIS116 |
| E | THR118 |
| E | ARG120 |
| E | HOH945 |
| site_id | GC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 267 |
| Chain | Residue |
| E | TYR40 |
| E | PRO52 |
| E | ALA56 |
| E | EDO298 |
| site_id | GC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO E 268 |
| Chain | Residue |
| E | ARG128 |
| E | ASP137 |
| E | GLU138 |
| E | THR152 |
| E | ILE153 |
| E | HOH363 |
| site_id | GC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO E 273 |
| Chain | Residue |
| E | ASN111 |
| E | LEU114 |
| E | ARG120 |
| E | ARG121 |
| E | GLN122 |
| E | LEU123 |
| E | CL256 |
| E | HOH1034 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO E 276 |
| Chain | Residue |
| E | ASP61 |
| F | GLU16 |
| F | ALA75 |
| F | ALA77 |
| F | THR83 |
| site_id | HC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 283 |
| Chain | Residue |
| E | LEU205 |
| E | PHE206 |
| E | ALA217 |
| E | HOH544 |
| site_id | HC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 288 |
| Chain | Residue |
| E | GLY163 |
| E | VAL164 |
| E | LEU165 |
| E | HOH777 |
| site_id | HC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 298 |
| Chain | Residue |
| E | PHE32 |
| E | ALA56 |
| E | SER60 |
| E | EDO267 |
| site_id | HC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO E 305 |
| Chain | Residue |
| E | ARG121 |
| E | THR125 |
| E | HOH363 |
| site_id | HC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD F 223 |
| Chain | Residue |
| F | GLU90 |
| F | ARG212 |
| site_id | HC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD F 228 |
| Chain | Residue |
| F | ARG31 |
| F | LEU214 |
| site_id | HC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD F 237 |
| Chain | Residue |
| F | ILE153 |
| F | ASN209 |
| F | ARG212 |
| site_id | HC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO F 297 |
| Chain | Residue |
| F | LEU107 |
| F | ASP108 |
| F | ASN111 |
| site_id | HC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO F 301 |
| Chain | Residue |
| F | PHE32 |
| F | ALA56 |
| F | SER60 |
| F | HOH1067 |
| site_id | IC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD G 224 |
| Chain | Residue |
| G | GLU90 |
| site_id | IC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD G 229 |
| Chain | Residue |
| G | ARG31 |
| G | LEU214 |
| site_id | IC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD G 238 |
| Chain | Residue |
| G | ILE153 |
| G | ASN209 |
| G | ARG212 |
| site_id | IC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL G 255 |
| Chain | Residue |
| G | ASP108 |
| G | ASN111 |
| G | LEU123 |
| site_id | IC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO G 262 |
| Chain | Residue |
| G | GLU16 |
| G | ALA75 |
| G | ASP81 |
| G | THR83 |
| H | ASP61 |
| site_id | IC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO G 300 |
| Chain | Residue |
| G | ASP33 |
| G | ARG34 |
| G | GLU182 |
| site_id | IC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO G 308 |
| Chain | Residue |
| G | LEU113 |
| G | HIS116 |
| G | THR118 |
| G | ARG120 |
| site_id | IC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD H 230 |
| Chain | Residue |
| H | ARG31 |
| H | LEU214 |
| site_id | IC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD H 235 |
| Chain | Residue |
| H | ILE153 |
| H | ASN209 |
| H | ARG212 |
| site_id | JC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD H 243 |
| Chain | Residue |
| H | ASP108 |
| H | ASN111 |
| H | LEU123 |
| site_id | JC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL H 249 |
| Chain | Residue |
| H | GLN24 |
| site_id | JC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL H 253 |
| Chain | Residue |
| H | ARG106 |
| site_id | JC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL H 254 |
| Chain | Residue |
| H | HOH1078 |
| site_id | JC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO H 274 |
| Chain | Residue |
| H | LEU113 |
| H | HIS116 |
| H | THR118 |
| H | ARG120 |
| H | HOH898 |
| site_id | JC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO H 281 |
| Chain | Residue |
| H | ARG121 |
| H | THR125 |
| H | HOH663 |
| site_id | JC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO H 311 |
| Chain | Residue |
| A | GLN53 |
Functional Information from PROSITE/UniProt
| site_id | PS00770 |
| Number of Residues | 31 |
| Details | AA_TRANSFER_CLASS_4 Aminotransferases class-IV signature. EgTitNVFadfgdgv.....LaTprldcgl.LpGVlR |
| Chain | Residue | Details |
| A | GLU150-ARG180 |
