3QQ0
Crystal structure of a deletion mutant (N59) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 280 |
| Chain | Residue |
| B | PRO136 |
| B | GLN137 |
| B | ARG164 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 281 |
| Chain | Residue |
| B | THR127 |
| B | HOH357 |
| B | HOH662 |
| B | HOH664 |
| B | HOH665 |
| C | GLU103 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 282 |
| Chain | Residue |
| B | HOH313 |
| B | HOH593 |
| B | HOH661 |
| B | HOH721 |
| B | HOH722 |
| C | HOH376 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 280 |
| Chain | Residue |
| C | ALA112 |
| C | GLN137 |
| C | ARG164 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 281 |
| Chain | Residue |
| C | GLN109 |
| C | LYS134 |
| C | HIS198 |
| C | PHE233 |
| C | HOH427 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 282 |
| Chain | Residue |
| C | ASN172 |
| C | LEU173 |
| C | HOH727 |
| D | ASP176 |
| D | LEU178 |
| D | HOH303 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 280 |
| Chain | Residue |
| D | ALA102 |
| D | THR127 |
| D | ASN129 |
| D | HOH723 |
| D | HOH724 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 281 |
| Chain | Residue |
| D | GLN109 |
| D | PHE233 |
| D | HOH456 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01406","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
