3QOF

Crystal structure of the cytosolic domain of human atlastin-1 in complex with GDP, orthorhombic form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GDP A 593

Chain	Residue
A	ALA75
A	ASP218
A	PRO272
A	VAL276
A	ASN279
A	PRO280
A	HOH458
A	MG595
A	PHE76
A	ARG77
A	LYS78
A	GLY79
A	LYS80
A	SER81
A	PHE82
A	ARG217

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 595

Chain	Residue
A	SER81
A	ASP146
A	GDP593

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GDP B 593

Chain	Residue
B	PHE76
B	ARG77
B	LYS78
B	GLY79
B	LYS80
B	SER81
B	PHE82
B	ARG217
B	ASP218
B	HIS271
B	PRO272
B	VAL276
B	ASN279
B	PRO280
B	MG595

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 595

Chain	Residue
B	SER81
B	ASP146
B	GLN148
B	GDP593

---

site_id	AC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GDP C 593

Chain	Residue
C	ARG77
C	LYS78
C	GLY79
C	LYS80
C	SER81
C	PHE82
C	ARG217
C	ASP218
C	HIS271
C	PRO272
C	VAL276
C	ASN279
C	PRO280
C	HOH449
C	HOH474
C	MG595

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 595

Chain	Residue
C	SER81
C	ASP146
C	GDP593

---

site_id	AC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GDP D 593

Chain	Residue
D	PHE76
D	ARG77
D	LYS78
D	GLY79
D	LYS80
D	SER81
D	PHE82
D	ARG217
D	ASP218
D	PRO272
D	VAL276
D	ASN279
D	HOH450
D	MG595

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 595

Chain	Residue
D	SER81
D	ARG113
D	ASP146
D	GLN148
D	GDP593

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	182
Details	Region: {"description":"3HB (three-helix bundle) domain","evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38509071","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4IDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IDP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QOF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PDB","id":"6XJN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QOF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6XJN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q6DD88","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	27
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---