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3QOB

Mechanical Coupling Controls Cooperative Ligand Binding in a Homodimeric Hemoglobin

Functional Information from GO Data
ChainGOidnamespacecontents
A0005344molecular_functionoxygen carrier activity
A0005737cellular_componentcytoplasm
A0015671biological_processoxygen transport
A0019825molecular_functionoxygen binding
A0020037molecular_functionheme binding
A0042802molecular_functionidentical protein binding
A0046872molecular_functionmetal ion binding
B0005344molecular_functionoxygen carrier activity
B0005737cellular_componentcytoplasm
B0015671biological_processoxygen transport
B0019825molecular_functionoxygen binding
B0020037molecular_functionheme binding
B0042802molecular_functionidentical protein binding
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues11
DetailsBINDING SITE FOR RESIDUE HEM A 147
ChainResidue
ATYR50
BLYS96
BASN100
APHE51
AARG53
ALEU73
APHE97
AHIS101
AARG104
APHE111
ACMO501

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CMO A 501
ChainResidue
ALEU40
ALEU73
AHEM147

site_idAC3
Number of Residues14
DetailsBINDING SITE FOR RESIDUE HEM B 147
ChainResidue
ALYS96
AASN100
BTYR50
BPHE51
BARG53
BHIS69
BALA76
BPHE97
BHIS101
BARG104
BGLU110
BPHE111
BILE114
BCMO501

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CMO B 501
ChainResidue
BLEU40
BPHE51
BHIS69
BLEU73
BILE114
BHEM147

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: proximal binding residue
ChainResidueDetails
AHIS101
BHIS101

227344

PDB entries from 2024-11-13

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