Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 100 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH105 |
| A | HOH156 |
| B | ARG41 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NI7 B 100 |
| Chain | Residue |
| A | ASP30 |
| A | VAL32 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | ILE84 |
| A | HOH149 |
| B | ASP25 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | VAL32 |
| B | GLY49 |
| B | ILE50 |
| B | HOH140 |
| B | HOH164 |
| B | HOH175 |
| B | HOH196 |
| B | HOH375 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 101 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 102 |
| Chain | Residue |
| B | THR74 |
| B | ASN88 |
| B | HOH154 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 138 |
| Details | Domain: {"description":"Peptidase A2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00275","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
