3QM0

Crystal structure of RTT109-AC-CoA complex

Replaces:  3D35

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004402	molecular_function	histone acetyltransferase activity
A	0005634	cellular_component	nucleus
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of DNA-templated transcription
A	0010484	molecular_function	histone H3 acetyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HG A 800

Chain	Residue
A	CYS94
A	THR96

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE HG A 801

Chain	Residue
A	GLU109
A	GLU232
A	CYS233

---

site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE ACO A 900

Chain	Residue
A	ARG97
A	VAL98
A	VAL100
A	ARG101
A	PHE192
A	THR193
A	ARG194
A	PRO195
A	ALA196
A	TYR199
A	LYS210
A	HIS211
A	ILE212
A	LEU213
A	LEU218
A	TRP221
A	TRP222
A	VAL85
A	ALA88
A	ASP89
A	THR90

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"18707894","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18568037","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18707894","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18719104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21256037","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZFN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CZ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q33","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q35","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QM0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18568037","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3QM0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18568037","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21256037","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q33","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q35","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QM0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18707894","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18719104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21256037","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZFN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CZ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q33","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q35","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; by autocatalysis","evidences":[{"source":"PubMed","id":"18568037","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18707894","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18719104","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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