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3QKX

Crystal structure of a TetR-family transcriptional regulator (HI0893) from Haemophilus influenzae RD at 2.35 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
B0000976molecular_functiontranscription cis-regulatory region binding
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues1
DetailsBINDING SITE FOR RESIDUE EDO A 202
ChainResidue
AASP127

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 205
ChainResidue
ASER176
AARG180
AHOH240

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 207
ChainResidue
ALEU28
ASER29
AMSE30
ALYS51

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 A 208
ChainResidue
ALYS89
AARG85

site_idAC5
Number of Residues1
DetailsBINDING SITE FOR RESIDUE SO4 A 209
ChainResidue
ALYS78

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CL B 201
ChainResidue
AGLY24
AASN26
BASN26
BGLN27

site_idAC7
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO B 203
ChainResidue
BPHE66
BPHE148
BLYS153

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 204
ChainResidue
BSER160
BALA162
BLYS163
BHOH251

site_idAC9
Number of Residues1
DetailsBINDING SITE FOR RESIDUE SO4 B 206
ChainResidue
BARG85

site_idBC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 B 210
ChainResidue
BSER176
BARG180

site_idBC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 B 211
ChainResidue
BTYR45
BASN50
BLYS51
BHOH213
BHOH228

Functional Information from PROSITE/UniProt
site_idPS01081
Number of Residues32
DetailsHTH_TETR_1 TetR-type HTH domain signature. GLnqlSMlkLakeanVAaGtIYlYFkNKdelL
ChainResidueDetails
AGLY24-LEU55

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues38
DetailsDNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335
ChainResidueDetails
ASER29-PHE48
BSER29-PHE48

226707

PDB entries from 2024-10-30

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