3QK8
Crystal structure of enoyl-coA hydratase EchA15 from Mycobacterium marinum in complex with an unknown ligand
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006631 | biological_process | fatty acid metabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0006631 | biological_process | fatty acid metabolic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| E | 0006629 | biological_process | lipid metabolic process |
| E | 0006631 | biological_process | fatty acid metabolic process |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| F | 0006629 | biological_process | lipid metabolic process |
| F | 0006631 | biological_process | fatty acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO F 297 |
| Chain | Residue |
| A | LYS163 |
| A | TYR166 |
| A | TYR167 |
| A | HOH704 |
| F | SER186 |
| F | THR187 |
| F | HOH601 |
| F | HOH1119 |
| F | HOH1263 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 305 |
| Chain | Residue |
| A | ASP103 |
| A | ASN211 |
| A | TRP215 |
| A | HOH293 |
| C | EDO301 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO C 297 |
| Chain | Residue |
| B | LYS163 |
| B | TYR166 |
| B | TYR167 |
| C | SER186 |
| C | THR187 |
| C | HOH286 |
| C | HOH296 |
| C | HOH533 |
| C | HOH635 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 301 |
| Chain | Residue |
| B | MET89 |
| B | ARG93 |
| B | HOH1195 |
| F | TRP215 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 305 |
| Chain | Residue |
| B | ASP103 |
| B | ASN211 |
| B | TRP215 |
| B | HOH904 |
| F | EDO301 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO E 297 |
| Chain | Residue |
| C | LYS163 |
| C | TYR166 |
| C | TYR167 |
| E | SER186 |
| E | THR187 |
| E | HOH1101 |
| F | HOH1049 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 301 |
| Chain | Residue |
| A | TRP215 |
| A | ARG218 |
| A | EDO305 |
| C | MET89 |
| C | ARG93 |
| C | HOH652 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 305 |
| Chain | Residue |
| A | EDO269 |
| C | ASP103 |
| C | ASN211 |
| C | TRP215 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 297 |
| Chain | Residue |
| A | SER186 |
| A | THR187 |
| A | HOH284 |
| A | HOH317 |
| A | HOH623 |
| A | HOH811 |
| D | LYS163 |
| D | TYR166 |
| D | TYR167 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 301 |
| Chain | Residue |
| D | MET89 |
| D | ARG90 |
| D | ARG93 |
| D | HOH1130 |
| D | HOH1142 |
| E | TRP215 |
| E | ARG218 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 305 |
| Chain | Residue |
| D | ASP103 |
| D | ASN211 |
| D | TRP215 |
| D | EDO269 |
| D | HOH1068 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 297 |
| Chain | Residue |
| B | SER186 |
| B | THR187 |
| B | HOH391 |
| B | HOH742 |
| B | HOH871 |
| B | HOH1182 |
| E | LYS163 |
| E | TYR166 |
| E | TYR167 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 269 |
| Chain | Residue |
| D | TRP215 |
| D | ARG218 |
| D | EDO305 |
| E | MET89 |
| E | ARG93 |
| E | HOH1085 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO D 297 |
| Chain | Residue |
| D | SER186 |
| D | THR187 |
| D | HOH713 |
| D | HOH1165 |
| D | HOH1233 |
| F | LYS163 |
| F | TYR166 |
| F | TYR167 |
| F | HOH271 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO F 301 |
| Chain | Residue |
| F | HOH646 |
| B | TRP215 |
| B | ARG218 |
| B | EDO305 |
| F | MET89 |
| F | ARG93 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL E 269 |
| Chain | Residue |
| E | GLY70 |
| E | GLY116 |
| E | ALA117 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 269 |
| Chain | Residue |
| A | MET89 |
| A | ARG90 |
| A | ARG93 |
| A | HOH583 |
| B | LEU237 |
| C | TRP215 |
| C | ARG218 |
| C | EDO305 |
Functional Information from PROSITE/UniProt
| site_id | PS00166 |
| Number of Residues | 21 |
| Details | ENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. VSaIRGpavGAGlvvaLlADI |
| Chain | Residue | Details |
| A | VAL107-ILE127 |
