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3QJA

Crystal Structure of the Mycobacterium tuberculosis Indole-3-glycerol phosphate synthase (TrpC) in apo form

Functional Information from GO Data
ChainGOidnamespacecontents
A0000162biological_processtryptophan biosynthetic process
A0000287molecular_functionmagnesium ion binding
A0004425molecular_functionindole-3-glycerol-phosphate synthase activity
A0004640molecular_functionphosphoribosylanthranilate isomerase activity
A0005886cellular_componentplasma membrane
A0006568biological_processtryptophan metabolic process
A0009274cellular_componentpeptidoglycan-based cell wall
A0016830molecular_functioncarbon-carbon lyase activity
A0016831molecular_functioncarboxy-lyase activity
A0046391biological_process5-phosphoribose 1-diphosphate metabolic process
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 A 273
ChainResidue
ALYS59
AARG191
ASER220
AGLY221
AGLY242
AGLU243
AHOH303
AHOH344

Functional Information from PROSITE/UniProt
site_idPS00614
Number of Residues18
DetailsIGPS Indole-3-glycerol phosphate synthase signature. VIaEVKRASPSagalat.I
ChainResidueDetails
AVAL54-ILE71

220472

PDB entries from 2024-05-29

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