3QJA

Crystal Structure of the Mycobacterium tuberculosis Indole-3-glycerol phosphate synthase (TrpC) in apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000162	biological_process	tryptophan biosynthetic process
A	0000287	molecular_function	magnesium ion binding
A	0004425	molecular_function	indole-3-glycerol-phosphate synthase activity
A	0004640	molecular_function	phosphoribosylanthranilate isomerase activity
A	0005886	cellular_component	plasma membrane
A	0006568	biological_process	tryptophan metabolic process
A	0006586	biological_process	indolalkylamine metabolic process
A	0009072	biological_process	aromatic amino acid metabolic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016830	molecular_function	carbon-carbon lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0046391	biological_process	5-phosphoribose 1-diphosphate metabolic process
A	1901605	biological_process	alpha-amino acid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 273

Chain	Residue
A	LYS59
A	ARG191
A	SER220
A	GLY221
A	GLY242
A	GLU243
A	HOH303
A	HOH344

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Functional Information from PROSITE/UniProt

site_id	PS00614
Number of Residues	18
Details	IGPS Indole-3-glycerol phosphate synthase signature. VIaEVKRASPSagalat.I

Chain	Residue	Details
A	VAL54-ILE71

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