3QF3

Crystal structure of EspR transcription factor from mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005576	cellular_component	extracellular region
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006351	biological_process	DNA-templated transcription
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0009295	cellular_component	nucleoid
A	0042802	molecular_function	identical protein binding
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0050708	biological_process	regulation of protein secretion
A	0052572	biological_process	response to host immune response
B	0003677	molecular_function	DNA binding
B	0005576	cellular_component	extracellular region
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006351	biological_process	DNA-templated transcription
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0009295	cellular_component	nucleoid
B	0042802	molecular_function	identical protein binding
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0050708	biological_process	regulation of protein secretion
B	0052572	biological_process	response to host immune response
C	0003677	molecular_function	DNA binding
C	0005576	cellular_component	extracellular region
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006351	biological_process	DNA-templated transcription
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0009295	cellular_component	nucleoid
C	0042802	molecular_function	identical protein binding
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0050708	biological_process	regulation of protein secretion
C	0052572	biological_process	response to host immune response
D	0003677	molecular_function	DNA binding
D	0005576	cellular_component	extracellular region
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006351	biological_process	DNA-templated transcription
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0009295	cellular_component	nucleoid
D	0042802	molecular_function	identical protein binding
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0050708	biological_process	regulation of protein secretion
D	0052572	biological_process	response to host immune response
E	0003677	molecular_function	DNA binding
E	0005576	cellular_component	extracellular region
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006351	biological_process	DNA-templated transcription
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0009295	cellular_component	nucleoid
E	0042802	molecular_function	identical protein binding
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0050708	biological_process	regulation of protein secretion
E	0052572	biological_process	response to host immune response
F	0003677	molecular_function	DNA binding
F	0005576	cellular_component	extracellular region
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006351	biological_process	DNA-templated transcription
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0009295	cellular_component	nucleoid
F	0042802	molecular_function	identical protein binding
F	0045893	biological_process	positive regulation of DNA-templated transcription
F	0050708	biological_process	regulation of protein secretion
F	0052572	biological_process	response to host immune response

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE LMR A 134

Chain	Residue
A	TYR18
A	PRO19
A	ARG70
D	VAL17
D	TYR18
D	PRO19
D	HIS25
D	PHE69

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE DMR B 134

Chain	Residue
B	TYR18
B	PRO19
B	PHE69
B	ARG70
B	HOH145
B	HOH212
B	HOH302
C	VAL17
C	PRO19
C	PHE69
C	ARG70
B	VAL17

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE DMR E 134

Chain	Residue
E	TYR18
E	PRO19
E	PRO20
E	HOH145
E	HOH155
E	HOH224
F	TYR18
F	PRO19

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	72
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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