3QCG

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0006470	biological_process	protein dephosphorylation
A	0016311	biological_process	dephosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE NX1 A 2001

Chain	Residue
A	ILE950
A	TYR1070
A	GLU1107
A	GLN1108
A	PHE1111
A	HOH2115
A	HOH2214
A	TYR1023
A	TRP1026
A	GLY1030
A	VAL1031
A	PRO1032
A	VAL1038
A	PHE1041
A	ARG1066

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACY A 2051

Chain	Residue
A	TYR880
A	ASN882
A	GLN1104

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Functional Information from PROSITE/UniProt

site_id	PS00383
Number of Residues	11
Details	TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGvgRTG

Chain	Residue	Details
A	VAL1058-GLY1068

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160, ECO:0000255|PROSITE-ProRule:PRU10044

Chain	Residue	Details
A	CYS1060

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP1028
A	GLN1104
A	CYS1060

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