3QCD

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with vanadate, trigonal crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0006470	biological_process	protein dephosphorylation
A	0016311	biological_process	dephosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE VO4 A 2001

Chain	Residue
A	ASP1028
A	HOH2101
A	HOH2102
A	CYS1060
A	SER1061
A	ALA1062
A	GLY1063
A	VAL1064
A	GLY1065
A	ARG1066
A	GLN1104

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACY A 2051

Chain	Residue
A	GLN845
A	GLN845
A	HOH2103
A	HOH2167
A	HOH2231

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACY A 2052

Chain	Residue
A	GLN856
A	ARG1096
A	TYR1101
A	HOH2218

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Functional Information from PROSITE/UniProt

site_id	PS00383
Number of Residues	11
Details	TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGvgRTG

Chain	Residue	Details
A	VAL1058-GLY1068

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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