3QAG
Human Glutathione Transferase O2 with glutathione -new crystal form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0006805 | biological_process | xenobiotic metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019852 | biological_process | L-ascorbic acid metabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0045174 | molecular_function | glutathione dehydrogenase (ascorbate) activity |
| A | 0050610 | molecular_function | methylarsonate reductase activity |
| A | 0055114 | biological_process | obsolete oxidation-reduction process |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071243 | biological_process | cellular response to arsenic-containing substance |
| A | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GSH A 1001 |
| Chain | Residue |
| A | CYS32 |
| A | HOH308 |
| A | HOH327 |
| A | TYR34 |
| A | LYS59 |
| A | HIS71 |
| A | ILE72 |
| A | PRO73 |
| A | GLU85 |
| A | SER86 |
| A | HOH249 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 1002 |
| Chain | Residue |
| A | LYS101 |
| A | LEU102 |
| A | PHE103 |
| A | GLY167 |
| A | SER172 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG A 1003 |
| Chain | Residue |
| A | TRP209 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 79 |
| Details | Domain: {"description":"GST N-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 125 |
| Details | Domain: {"description":"GST C-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22522127","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
