Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 337 |
| Chain | Residue |
| A | ARG80 |
| A | ARG155 |
| A | ASN189 |
| A | VAL192 |
| A | HOH356 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 338 |
| Chain | Residue |
| A | HIS276 |
| A | SER277 |
| A | LYS279 |
| A | HOH441 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 339 |
| Chain | Residue |
| A | TRP33 |
| A | LYS75 |
| A | HOH355 |
| A | HOH404 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 340 |
| Chain | Residue |
| A | GLY48 |
| A | LYS49 |
| A | TYR50 |
| A | SER51 |
| A | LYS68 |
| A | ASP175 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 341 |
| Chain | Residue |
| A | GLU252 |
| A | ARG278 |
| A | HOH411 |
| B | GLU252 |
| B | ARG278 |
| B | HOH389 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 342 |
| Chain | Residue |
| A | ASP25 |
| A | TYR26 |
| A | GLU27 |
| A | LYS44 |
| A | HOH453 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 337 |
| Chain | Residue |
| B | ARG80 |
| B | ARG155 |
| B | ASN189 |
| B | HOH356 |
| B | HOH361 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 338 |
| Chain | Residue |
| B | LYS279 |
| B | ARG280 |
| B | HOH347 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 339 |
| Chain | Residue |
| B | ARG191 |
| B | LYS198 |
| B | ASN238 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 340 |
| Chain | Residue |
| B | TRP33 |
| B | LYS75 |
| B | LYS102 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 341 |
| Chain | Residue |
| B | GLN36 |
| B | TYR39 |
| B | ASP103 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 342 |
| Chain | Residue |
| B | HIS276 |
| B | SER277 |
| B | LYS279 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
| Chain | Residue | Details |
| A | LEU45-LYS68 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 570 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
