Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004347 | molecular_function | glucose-6-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0048029 | molecular_function | monosaccharide binding |
| A | 0051156 | biological_process | glucose 6-phosphate metabolic process |
| A | 0097367 | molecular_function | carbohydrate derivative binding |
| A | 1901135 | biological_process | carbohydrate derivative metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE 6PG A 601 |
| Chain | Residue |
| A | ILE145 |
| A | ARG261 |
| A | GLN342 |
| A | GLU346 |
| A | HIS377 |
| A | GLN498 |
| A | LYS505 |
| A | HOH567 |
| A | HOH626 |
| A | HOH661 |
| A | HOH816 |
| A | GLY146 |
| A | HOH922 |
| A | HOH923 |
| A | HOH978 |
| A | GLY147 |
| A | SER148 |
| A | SER198 |
| A | LYS199 |
| A | SER200 |
| A | THR203 |
| A | GLY260 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MES A 602 |
| Chain | Residue |
| A | ASN74 |
| A | PRO98 |
| A | LEU99 |
| A | ILE100 |
| A | HIS401 |
| A | HIS402 |
| A | ASN403 |
| A | HOH998 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MES A 603 |
| Chain | Residue |
| A | GLN160 |
| A | PRO161 |
| A | HIS163 |
| A | GLN182 |
| A | HIS185 |
| A | HIS401 |
| A | HOH621 |
| A | HOH874 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 604 |
| Chain | Residue |
| A | ASN38 |
| A | TYR40 |
| A | LEU464 |
| A | ASP466 |
| A | LYS536 |
| A | HOH1032 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IPA A 605 |
| Chain | Residue |
| A | HIS36 |
| A | GLN37 |
| A | ASN38 |
| A | TYR471 |
| A | SER472 |
| A | ALA475 |
| A | HOH800 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 606 |
| Chain | Residue |
| A | GLU61 |
| A | GLU222 |
| A | HOH573 |
| A | HOH574 |
| A | HOH592 |
| A | HOH982 |
Functional Information from PROSITE/UniProt
| site_id | PS00174 |
| Number of Residues | 18 |
| Details | P_GLUCOSE_ISOMERASE_2 Phosphoglucose isomerase signature 2. GvLWdinsYDQwGVElgK |
| Chain | Residue | Details |
| A | GLY488-LYS505 | |
| site_id | PS00765 |
| Number of Residues | 14 |
| Details | P_GLUCOSE_ISOMERASE_1 Phosphoglucose isomerase signature 1. DwVGGRYSLwSSIG |
| Chain | Residue | Details |
| A | ASP256-GLY269 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00473","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00473","evidenceCode":"ECO:0000255"}]} |
3Q7I
