Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE RIT A 2001 |
| Chain | Residue |
| A | ASP32 |
| A | ASP218 |
| A | GLY220 |
| A | THR221 |
| A | THR222 |
| A | TYR225 |
| A | ILE305 |
| A | HOH6004 |
| A | HOH6106 |
| A | HOH6173 |
| A | GLY34 |
| A | SER35 |
| A | GLY83 |
| A | TYR84 |
| A | GLY85 |
| A | ILE119 |
| A | ASP120 |
| A | ASN131 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 3000 |
| Chain | Residue |
| A | ASP57 |
| A | GLU324 |
| A | HOH6195 |
| A | HOH6204 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 3001 |
| Chain | Residue |
| A | HOH6196 |
| A | HOH6199 |
| A | HOH6200 |
| A | HOH6201 |
| A | HOH6202 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MRD A 4001 |
| Chain | Residue |
| A | LEU183 |
| A | SER326 |
| A | HOH6024 |
| A | HOH6058 |
| A | HOH6137 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIVDTGSSDLWV |
| Chain | Residue | Details |
| A | VAL29-VAL40 | |
| A | VAL215-LEU226 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP32 | |
| A | ASP218 | |
| Chain | Residue | Details |
| A | ASP32 | |
| A | GLY85 | |
| A | ASP191 | |
| A | ASP214 | |
| A | ASP218 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN257 | |
| A | ASN265 | |
