3Q4K

Structure of a small peptide ligand bound to E.coli DNA sliding clamp

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006271	biological_process	DNA strand elongation involved in DNA replication
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0009360	cellular_component	DNA polymerase III complex
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0030174	biological_process	regulation of DNA-templated DNA replication initiation
A	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
A	0042276	biological_process	error-prone translesion synthesis
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0044787	biological_process	bacterial-type DNA replication
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006271	biological_process	DNA strand elongation involved in DNA replication
B	0006974	biological_process	DNA damage response
B	0008408	molecular_function	3'-5' exonuclease activity
B	0009360	cellular_component	DNA polymerase III complex
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0030174	biological_process	regulation of DNA-templated DNA replication initiation
B	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
B	0042276	biological_process	error-prone translesion synthesis
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0044787	biological_process	bacterial-type DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR CHAIN C OF PEPTIDE LIGAND

Chain	Residue
A	THR172
A	MET362
A	PRO363
A	MET364
A	ARG365
A	HOH433
B	LYS250
B	ASN251
A	GLY174
A	HIS175
A	ARG176
A	PRO242
A	ASP243
A	VAL247
A	VAL344
A	ALA353

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR CHAIN D OF PEPTIDE LIGAND

Chain	Residue
B	THR172
B	GLY174
B	HIS175
B	ARG176
B	LEU177
B	VAL247
B	VAL344
B	VAL360
B	MET362
B	PRO363
B	MET364
B	ARG365

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	228
Details	Region: {"description":"2","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18191219","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18191219","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	120
Details	Region: {"description":"3","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---