3Q3O

Toluene 4 monooxygenase HD complex with phenol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0018638	molecular_function	toluene 4-monooxygenase activity
A	0042203	biological_process	toluene catabolic process
A	0046872	molecular_function	metal ion binding
B	0004497	molecular_function	monooxygenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
B	0018638	molecular_function	toluene 4-monooxygenase activity
B	0042203	biological_process	toluene catabolic process
C	0004497	molecular_function	monooxygenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0018638	molecular_function	toluene 4-monooxygenase activity
C	0042203	biological_process	toluene catabolic process
E	0004497	molecular_function	monooxygenase activity
E	0042203	biological_process	toluene catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 501

Chain	Residue
A	GLU104
A	GLU134
A	HIS137
A	FE502
A	IPH503
A	HOH511
A	HOH522

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 502

Chain	Residue
A	GLU231
A	HIS234
A	FE501
A	IPH503
A	HOH511
A	GLU134
A	GLU197

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE IPH A 503

Chain	Residue
A	GLU104
A	ALA107
A	GLU134
A	PHE176
A	GLU197
A	GLU231
A	FE501
A	FE502
A	HOH511

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE IPH A 504

Chain	Residue
A	TRP167
A	TRP338
A	THR341
A	PRO394
A	VAL396
A	ILE450
A	IPH505

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE IPH A 505

Chain	Residue
A	TRP167
A	GLY334
A	VAL335
A	TRP338
A	PRO403
A	IPH504
A	HOH595

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IPH A 506

Chain	Residue
A	HIS4
A	PRO5
A	ARG6
A	TRP9
A	HOH583
A	HOH631

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IPH A 507

Chain	Residue
A	ALA99
A	ILE100
A	PHE176
A	GLN204
A	LEU268
A	PHE269
A	LEU272
A	THR273

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IPH B 308

Chain	Residue
A	PRO56
B	GLU91
B	GLN95
B	THR164
B	HIS165
B	HOH312

---

site_id	AC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE 1PE B 309

Chain	Residue
A	ARG63
A	ARG63
B	LEU85
B	LEU85
B	ASP88
B	ASP88
B	GLY89
B	SER92
B	SER92
B	HOH547
B	HOH547

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19033467","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19290655","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19705873","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22264099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25248368","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28346937","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RI7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RMK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P1B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P1C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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