3Q1O
Crystal structure of geranyltransferase from helicobacter pylori complexed with magnesium and isoprenyl diphosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016114 | biological_process | terpenoid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004659 | molecular_function | prenyltransferase activity |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016114 | biological_process | terpenoid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004659 | molecular_function | prenyltransferase activity |
| C | 0008299 | biological_process | isoprenoid biosynthetic process |
| C | 0016114 | biological_process | terpenoid biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004659 | molecular_function | prenyltransferase activity |
| D | 0008299 | biological_process | isoprenoid biosynthetic process |
| D | 0016114 | biological_process | terpenoid biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 400 |
| Chain | Residue |
| A | ASP92 |
| A | ASP98 |
| A | HOH312 |
| A | HOH313 |
| A | DMA501 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE DMA A 500 |
| Chain | Residue |
| A | ARG104 |
| A | THR187 |
| A | PHE224 |
| A | GLN225 |
| A | ASP228 |
| A | HOH306 |
| A | HOH308 |
| A | HOH330 |
| A | HOH352 |
| A | HOH353 |
| A | HOH354 |
| A | DMA501 |
| A | GLY46 |
| A | LYS47 |
| A | ARG50 |
| A | HIS85 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE DMA A 501 |
| Chain | Residue |
| A | SER88 |
| A | ASP92 |
| A | ASP98 |
| A | ARG103 |
| A | GLN163 |
| A | LYS186 |
| A | GLN225 |
| A | ASP228 |
| A | LYS242 |
| A | HOH313 |
| A | HOH314 |
| A | HOH319 |
| A | HOH320 |
| A | HOH356 |
| A | HOH382 |
| A | MG400 |
| A | DMA500 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | GLU139 |
| A | SER140 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | ASN11 |
| A | ARG15 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | SER18 |
| A | LYS21 |
| A | ASN22 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 400 |
| Chain | Residue |
| B | ASP92 |
| B | ASP98 |
| B | HOH314 |
| B | HOH343 |
| B | DMA501 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE DMA B 500 |
| Chain | Residue |
| B | GLY46 |
| B | LYS47 |
| B | ARG50 |
| B | HIS85 |
| B | ARG104 |
| B | THR187 |
| B | PHE224 |
| B | GLN225 |
| B | ASP228 |
| B | HOH308 |
| B | HOH309 |
| B | HOH334 |
| B | HOH335 |
| B | HOH336 |
| B | DMA501 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE DMA B 501 |
| Chain | Residue |
| B | SER88 |
| B | LEU89 |
| B | ASP92 |
| B | ASP98 |
| B | ARG103 |
| B | GLN163 |
| B | LYS186 |
| B | ASP228 |
| B | LYS242 |
| B | HIS245 |
| B | HOH314 |
| B | HOH316 |
| B | HOH333 |
| B | HOH337 |
| B | HOH359 |
| B | MG400 |
| B | DMA500 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | GLN267 |
| B | LYS270 |
| B | PHE299 |
| B | LYS300 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 400 |
| Chain | Residue |
| C | ASP92 |
| C | ASP98 |
| C | ARG103 |
| C | HOH323 |
| C | HOH325 |
| C | DMA501 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 401 |
| Chain | Residue |
| C | ASP228 |
| C | HOH322 |
| C | HOH345 |
| C | DMA501 |
| site_id | BC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE DMA C 500 |
| Chain | Residue |
| C | HIS85 |
| C | ARG104 |
| C | THR187 |
| C | PHE224 |
| C | GLN225 |
| C | ASP228 |
| C | HOH311 |
| C | HOH313 |
| C | HOH317 |
| C | HOH328 |
| C | HOH350 |
| C | HOH352 |
| C | DMA501 |
| C | GLY46 |
| C | LYS47 |
| C | ARG50 |
| site_id | BC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE DMA C 501 |
| Chain | Residue |
| C | SER88 |
| C | ASP92 |
| C | ASP98 |
| C | ARG103 |
| C | GLN163 |
| C | LYS186 |
| C | ASP228 |
| C | LYS242 |
| C | HOH322 |
| C | HOH323 |
| C | HOH324 |
| C | HOH325 |
| C | HOH326 |
| C | HOH327 |
| C | HOH345 |
| C | MG400 |
| C | MG401 |
| C | DMA500 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 302 |
| Chain | Residue |
| C | ALA60 |
| C | TYR284 |
| C | PRO285 |
| C | LEU286 |
| C | LEU287 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 303 |
| Chain | Residue |
| C | ASN11 |
| C | ARG15 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 304 |
| Chain | Residue |
| C | SER18 |
| C | LYS21 |
| C | ASN22 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 400 |
| Chain | Residue |
| D | ASP92 |
| D | ASP98 |
| D | ARG103 |
| D | HOH311 |
| D | DMA501 |
| site_id | CC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE DMA D 500 |
| Chain | Residue |
| D | GLY46 |
| D | LYS47 |
| D | ARG50 |
| D | HIS85 |
| D | ARG104 |
| D | THR187 |
| D | PHE224 |
| D | GLN225 |
| D | ASP228 |
| D | HOH316 |
| D | HOH317 |
| D | DMA501 |
| site_id | CC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE DMA D 501 |
| Chain | Residue |
| D | SER88 |
| D | ASP92 |
| D | ASP98 |
| D | ARG103 |
| D | LYS186 |
| D | LYS242 |
| D | HOH310 |
| D | HOH312 |
| D | HOH313 |
| D | HOH319 |
| D | HOH320 |
| D | MG400 |
| D | DMA500 |
Functional Information from PROSITE/UniProt
| site_id | PS00444 |
| Number of Residues | 13 |
| Details | POLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. MGlcFQVlDDIiD |
| Chain | Residue | Details |
| A | MET220-ASP232 |
