3Q12
Pantoate-beta-alanine ligase from Yersinia pestis in complex with pantoate.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004592 | molecular_function | pantoate-beta-alanine ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0015940 | biological_process | pantothenate biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| B | 0004592 | molecular_function | pantoate-beta-alanine ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0015940 | biological_process | pantothenate biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| C | 0004592 | molecular_function | pantoate-beta-alanine ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0015940 | biological_process | pantothenate biosynthetic process |
| C | 0016874 | molecular_function | ligase activity |
| D | 0004592 | molecular_function | pantoate-beta-alanine ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0015940 | biological_process | pantothenate biosynthetic process |
| D | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PAF A 501 |
| Chain | Residue |
| A | PRO28 |
| A | THR29 |
| A | GLN61 |
| A | ILE133 |
| A | GLN155 |
| A | HOH289 |
| A | HOH704 |
| A | HOH866 |
| A | HOH867 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 285 |
| Chain | Residue |
| A | GLN61 |
| A | ARG123 |
| A | HIS126 |
| A | ARG189 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PAF B 501 |
| Chain | Residue |
| B | PRO28 |
| B | THR29 |
| B | GLN61 |
| B | ILE133 |
| B | GLN155 |
| B | HOH303 |
| B | HOH312 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PAF C 501 |
| Chain | Residue |
| C | PRO28 |
| C | THR29 |
| C | MET30 |
| C | GLN61 |
| C | ILE133 |
| C | GLN155 |
| C | HOH293 |
| C | HOH798 |
| C | HOH800 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 285 |
| Chain | Residue |
| C | GLN61 |
| C | ARG123 |
| C | HIS126 |
| C | ARG189 |
| C | HOH1028 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PAF D 501 |
| Chain | Residue |
| D | PRO28 |
| D | THR29 |
| D | GLN61 |
| D | ILE133 |
| D | GLN155 |
| D | HOH782 |
| D | HOH811 |
| D | HOH812 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00158 |
| Chain | Residue | Details |
| A | HIS37 | |
| B | HIS37 | |
| C | HIS37 | |
| D | HIS37 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00158 |
| Chain | Residue | Details |
| A | MET30 | |
| B | GLN155 | |
| B | VAL178 | |
| B | LEU186 | |
| C | MET30 | |
| C | GLN61 | |
| C | GLY149 | |
| C | GLN155 | |
| C | VAL178 | |
| C | LEU186 | |
| D | MET30 | |
| A | GLN61 | |
| D | GLN61 | |
| D | GLY149 | |
| D | GLN155 | |
| D | VAL178 | |
| D | LEU186 | |
| A | GLY149 | |
| A | GLN155 | |
| A | VAL178 | |
| A | LEU186 | |
| B | MET30 | |
| B | GLN61 | |
| B | GLY149 |
