3Q10

Pantoate-beta-alanine ligase from Yersinia pestis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004592	molecular_function	pantoate-beta-alanine ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0015940	biological_process	pantothenate biosynthetic process
A	0016874	molecular_function	ligase activity
B	0000166	molecular_function	nucleotide binding
B	0004592	molecular_function	pantoate-beta-alanine ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0015940	biological_process	pantothenate biosynthetic process
B	0016874	molecular_function	ligase activity
C	0000166	molecular_function	nucleotide binding
C	0004592	molecular_function	pantoate-beta-alanine ligase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0015940	biological_process	pantothenate biosynthetic process
C	0016874	molecular_function	ligase activity
D	0000166	molecular_function	nucleotide binding
D	0004592	molecular_function	pantoate-beta-alanine ligase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0015940	biological_process	pantothenate biosynthetic process
D	0016874	molecular_function	ligase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE AMP A 501

Chain	Residue
A	PRO28
A	THR177
A	VAL178
A	LEU186
A	HOH358
A	HOH376
A	HOH386
A	HOH414
A	HOH417
A	HOH436
A	GOL601
A	MET30
A	HOH615
A	HIS34
A	HIS37
A	LEU40
A	PHE148
A	GLY149
A	ASP152
A	PRO176

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE AMP B 501

Chain	Residue
B	PRO28
B	MET30
B	HIS34
B	HIS37
B	LEU40
B	PHE148
B	GLY149
B	ASP152
B	PRO176
B	THR177
B	VAL178
B	LEU186
B	HOH285
B	HOH311
B	HOH338
B	HOH340
B	HOH362
B	GOL603

---

site_id	AC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE AMP C 501

Chain	Residue
C	HIS34
C	HIS37
C	LEU40
C	PHE148
C	GLY149
C	LYS151
C	ASP152
C	PRO176
C	THR177
C	VAL178
C	LEU186
C	HOH290
C	HOH520
C	GOL602
C	HOH603
C	HOH604
C	HOH652
C	HOH675

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE AMP D 501

Chain	Residue
D	PRO28
D	MET30
D	HIS37
D	LEU40
D	PHE148
D	GLY149
D	THR177
D	HOH300
D	GOL604

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 601

Chain	Residue
A	MET30
A	GLN61
A	VAL130
A	ILE133
A	GLN155
A	HOH306
A	AMP501

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 602

Chain	Residue
C	GLN61
C	ILE133
C	GLN155
C	HOH294
C	AMP501

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 603

Chain	Residue
B	MET30
B	GLN61
B	ILE133
B	GLN155
B	HOH294
B	AMP501

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 604

Chain	Residue
D	THR29
D	GLN61
D	VAL130
D	GLN155
D	AMP501
D	HOH653

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL B 605

Chain	Residue
B	GLN260
B	HOH343
B	HOH664

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IMD A 606

Chain	Residue
A	TYR153
A	GLN260
A	HOH616

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 607

Chain	Residue
A	HOH673
A	GLN61
A	ARG123
A	HIS126
A	ARG189

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00158","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00158","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---