3Q0O

Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with erk2 NRE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
B	0003723	molecular_function	RNA binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	340
Details	Domain: {"description":"PUM-HD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	70
Details	Repeat: {"description":"Pumilio 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	70
Details	Repeat: {"description":"Pumilio 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	70
Details	Repeat: {"description":"Pumilio 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	70
Details	Repeat: {"description":"Pumilio 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	70
Details	Repeat: {"description":"Pumilio 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	70
Details	Repeat: {"description":"Pumilio 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	70
Details	Repeat: {"description":"Pumilio 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	39
Details	Repeat: {"description":"Pumilio 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI10
Number of Residues	24
Details	Region: {"description":"Adenine-nucleotide binding in RNA target","evidences":[{"source":"PubMed","id":"18328718","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI11
Number of Residues	8
Details	Region: {"description":"Uracil-nucleotide binding in RNA target","evidences":[{"source":"PubMed","id":"18328718","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI12
Number of Residues	8
Details	Region: {"description":"Non-specific-nucleotide binding in RNA target","evidences":[{"source":"PubMed","id":"18328718","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI13
Number of Residues	8
Details	Region: {"description":"Uracil-nucleotide binding in RNA target","evidences":[{"source":"PubMed","id":"18328718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BSB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI14
Number of Residues	8
Details	Region: {"description":"Guanine-nucleotide binding in RNA target","evidences":[{"source":"PubMed","id":"18328718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BSB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI15
Number of Residues	8
Details	Region: {"description":"Uracil-nucleotide binding in RNA target","evidences":[{"source":"PubMed","id":"18328718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1M8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1M8X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BSB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BSX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q0L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q0N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q0O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q0P","evidenceCode":"ECO:0007744"}]}

Chain

Residue

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