Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005506 | molecular_function | iron ion binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006633 | biological_process | fatty acid biosynthetic process |
A | 0016165 | molecular_function | linoleate 13S-lipoxygenase activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
A | 0019395 | biological_process | fatty acid oxidation |
A | 0031408 | biological_process | oxylipin biosynthetic process |
A | 0034440 | biological_process | lipid oxidation |
A | 0046872 | molecular_function | metal ion binding |
A | 0051213 | molecular_function | dioxygenase activity |
A | 0102299 | molecular_function | linolenate 9R-lipoxygenase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE FE2 A 840 |
Chain | Residue |
A | HIS499 |
A | HIS504 |
A | HIS690 |
A | ASN694 |
A | ILE839 |
A | HOH870 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO A 841 |
Chain | Residue |
A | HIS147 |
A | VAL520 |
A | LYS526 |
A | HOH1056 |
A | HOH1406 |
A | VAL126 |
A | ALA145 |
A | ASN146 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 842 |
Chain | Residue |
A | ASP291 |
A | GLY295 |
A | GLY296 |
A | LYS298 |
A | HOH936 |
A | HOH1108 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 843 |
Chain | Residue |
A | ILE412 |
A | ALA569 |
A | HOH1012 |
A | HOH1173 |
A | HOH1260 |
site_id | AC5 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE EDO A 844 |
Chain | Residue |
A | PHE346 |
A | ALA484 |
A | ILE487 |
A | MET705 |
A | ASN706 |
A | PRO708 |
A | TYR734 |
A | HOH847 |
A | HOH874 |
site_id | AC6 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE ACT A 845 |
Chain | Residue |
A | ASP440 |
A | THR442 |
A | ASP607 |
A | SER804 |
A | LEU805 |
A | GLY807 |
A | ASN808 |
A | HOH1346 |
A | HOH1748 |
Functional Information from PROSITE/UniProt
site_id | PS00081 |
Number of Residues | 11 |
Details | LIPOXYGENASE_2 Lipoxygenases iron-binding region signature 2. LHPIyKLLtPH |
Chain | Residue | Details |
A | LEU521-HIS531 | |
site_id | PS00711 |
Number of Residues | 15 |
Details | LIPOXYGENASE_1 Lipoxygenases iron-binding region signature 1. HQlmsHwLNTHAAmE |
Chain | Residue | Details |
A | HIS494-GLU508 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS499 | |
A | HIS504 | |
A | HIS690 | |
A | ASN694 | |
Chain | Residue | Details |
A | ILE839 | |