3PYF

Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) in complex with AMP-PNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016114	biological_process	terpenoid biosynthetic process
A	0016301	molecular_function	kinase activity
A	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
A	0050515	molecular_function	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ANP A 307

Chain	Residue
A	LEU64
A	GLY105
A	GLY106
A	ASP109
A	ASP140
A	SER269
A	HOH317
A	HOH318
A	HOH350
A	HOH371
A	HOH407
A	ASN70
A	LEU71
A	VAL99
A	ALA100
A	GLY101
A	GLY102
A	MET103
A	ALA104

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00061

Chain	Residue	Details
A	GLU25
A	GLY152

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00061

Chain	Residue	Details
A	ALA110

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