Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ROC A 401 |
| Chain | Residue |
| A | TRP6 |
| A | ILE50 |
| A | THR80 |
| A | PRO81 |
| A | ILE84 |
| B | ARG108 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| B | ASP130 |
| A | ARG8 |
| B | ILE147 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | PRO181 |
| B | VAL182 |
| B | ILE184 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | GLY48 |
| A | GLY49 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 501 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| B | ARG141 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 801 |
| Chain | Residue |
| A | THR4 |
| A | LEU5 |
| A | TRP6 |
| B | THR191 |
| B | ALA195 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 804 |
| Chain | Residue |
| A | PRO39 |
| A | GLY40 |
| A | ARG41 |
| A | TYR59 |
| A | ASP60 |
| A | GLN61 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 805 |
| Chain | Residue |
| A | ASP29 |
| A | ASP30 |
| A | THR74 |
| A | ASN88 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 806 |
| Chain | Residue |
| A | ASP29 |
| A | ARG87 |
| B | TRP106 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 807 |
| Chain | Residue |
| A | ILE15 |
| A | GLY16 |
| A | GLN61 |
| A | ILE62 |
| A | ILE63 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 808 |
| Chain | Residue |
| A | ASP29 |
| A | ILE47 |
| A | GLY48 |
| A | ROC401 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 802 |
| Chain | Residue |
| B | GLY116 |
| B | LEU138 |
| B | PRO139 |
| B | ILE162 |
| B | ILE163 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 803 |
| Chain | Residue |
| A | TRP6 |
| B | ASP129 |
| B | ARG187 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE199 | |
