3PW7

Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV and incoming dCTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0003677	molecular_function	DNA binding
E	0003684	molecular_function	damaged DNA binding
E	0003887	molecular_function	DNA-directed DNA polymerase activity
E	0005737	cellular_component	cytoplasm
E	0006260	biological_process	DNA replication
E	0006261	biological_process	DNA-templated DNA replication
E	0006281	biological_process	DNA repair
E	0006974	biological_process	DNA damage response
E	0042276	biological_process	error-prone translesion synthesis
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DCP A 400

Chain	Residue
A	ASP10
A	CA345
A	HOH500
A	HOH501
A	HOH502
A	HOH505
C	DT358
C	HOH500
A	PHE11
A	TYR13
A	PHE14
A	ARG54
A	SER106
A	ASP108
A	GLU109
A	LYS162

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 345

Chain	Residue
A	TYR51
A	ARG54
A	LYS162
A	DCP400

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE DCP E 400

Chain	Residue
E	ASP10
E	PHE11
E	SER106
E	ASP108
E	GLU109
E	LYS162
E	HOH524
E	HOH528
E	HOH529
E	HOH530
E	HOH531
G	DT358

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA E 345

Chain	Residue
E	ALA184
E	ILE189

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE:

Chain	Residue	Details
A	GLU109
E	GLU109

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
A	ASP10
A	ASP108
E	ASP10
E	ASP108

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Substrate discrimination

Chain	Residue	Details
A	TYR15
E	TYR15

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