3PS3

Crystal structure of the Escherichia Coli LPXC/LPC-053 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008759	molecular_function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A	0009245	biological_process	lipid A biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 301

Chain	Residue
A	HIS79
A	HIS238
A	ASP242
A	L53401

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site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE L53 A 401

Chain	Residue
A	THR191
A	PHE192
A	ILE198
A	GLN202
A	GLY210
A	SER211
A	PHE212
A	HIS238
A	ASP242
A	HIS265
A	ZN301
A	DMS601
A	SO4704
A	LEU18
A	LEU62
A	CYS63
A	GLU78
A	HIS79

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site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE UKW A 501

Chain	Residue
A	TYR113
A	LEU116
A	MET183
A	ARG184
A	SER187
A	ARG188
A	PHE194
A	ASP197
A	TYR200
A	LEU201
A	HOH1006
A	HOH1033
A	HOH1064

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE DMS A 601

Chain	Residue
A	ASP197
A	L53401

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DMS A 602

Chain	Residue
A	ILE166
A	GLY193
A	PHE194

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site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 701

Chain	Residue
A	LYS22
A	GLU122
A	LEU123
A	ASN124
A	HOH1102

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 702

Chain	Residue
A	HIS252
A	LEU276
A	TRP282
A	TYR284

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 703

Chain	Residue
A	THR60
A	MET61
A	ARG73
A	HOH1078

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site_id	AC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 704

Chain	Residue
A	ASP59
A	LYS239
A	GLY264
A	HIS265
A	L53401
A	HOH1002
A	HOH1058
A	HOH1068
A	HOH1096

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site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 705

Chain	Residue
A	LYS22
A	LYS23
A	HOH1111

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