3PRT

Mutant of the Carboxypeptidase T

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004181	molecular_function	metallocarboxypeptidase activity
A	0006508	biological_process	proteolysis
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 324

Chain	Residue
A	HIS69
A	ARG129
A	ASN146
A	ARG147
A	TYR255
A	GLU277
A	GOL326
A	GOL331
A	HOH525

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 400

Chain	Residue
A	HIS69
A	GLU72
A	HIS204
A	HOH525

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	ASP56
A	GLU57
A	GLU61
A	GLU104
A	HOH555
A	HOH556

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 402

Chain	Residue
A	SER50
A	ASP51
A	GLU57
A	GLU59
A	CA403
A	HOH495

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 403

Chain	Residue
A	ASP51
A	GLU57
A	GLU59
A	ASN101
A	CA402
A	HOH478

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 404

Chain	Residue
A	SER7
A	TYR9
A	GLU14
A	HOH424
A	HOH533

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 325

Chain	Residue
A	VAL16
A	ASN20
A	ASN25
A	LYS32
A	TRP45
A	HOH342

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 326

Chain	Residue
A	ASN146
A	SER215
A	GLY251
A	TYR255
A	ALA257
A	ASP262
A	SO4324
A	HOH339

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 327

Chain	Residue
A	PHE174
A	ARG183
A	ASN187
A	TRP264
A	GLN268
A	HOH527
A	HOH552

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 328

Chain	Residue
A	TYR118
A	ARG132
A	HOH350
A	HOH560
A	HOH561

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 329

Chain	Residue
A	LYS270
A	HOH358
A	HOH375

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 330

Chain	Residue
A	ARG71
A	LYS152
A	CYS156
A	HOH416

---

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 331

Chain	Residue
A	ARG129
A	THR205
A	TYR206
A	TYR255
A	GLU277
A	PHE287
A	SO4324
A	HOH361

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 332

Chain	Residue
A	ASN52
A	VAL53
A	GLY54
A	THR55
A	HOH412

---

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 333

Chain	Residue
A	GLY295
A	ARG296
A	HOH355

---

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 334

Chain	Residue
A	HIS10
A	GLU77
A	LEU80
A	TYR81
A	ASP84
A	ILE294
A	HOH467
A	HOH537

---

Functional Information from PROSITE/UniProt

site_id	PS00132
Number of Residues	23
Details	CARBOXYPEPT_ZN_1 Zinc carboxypeptidases, zinc-binding region 1 signature. PeVlYtaLhHArEhLTVemalyT

Chain	Residue	Details
A	PRO60-THR82

---

site_id	PS00133
Number of Residues	11
Details	CARBOXYPEPT_ZN_2 Zinc carboxypeptidases, zinc-binding region 2 signature. HTYSELIlYPY

Chain	Residue	Details
A	HIS204-TYR214

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	304
Details	Domain: {"description":"Peptidase M14","evidences":[{"source":"PROSITE-ProRule","id":"PRU01379","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01379","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1521526","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01379","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1521526","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---