3PQV
Cyclase homolog
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000479 | biological_process | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005730 | cellular_component | nucleolus |
| A | 0006396 | biological_process | RNA processing |
| A | 0042254 | biological_process | ribosome biogenesis |
| B | 0000479 | biological_process | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005730 | cellular_component | nucleolus |
| B | 0006396 | biological_process | RNA processing |
| B | 0042254 | biological_process | ribosome biogenesis |
| C | 0000479 | biological_process | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004521 | molecular_function | RNA endonuclease activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0005730 | cellular_component | nucleolus |
| C | 0006396 | biological_process | RNA processing |
| C | 0042254 | biological_process | ribosome biogenesis |
| D | 0000479 | biological_process | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004521 | molecular_function | RNA endonuclease activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0005730 | cellular_component | nucleolus |
| D | 0006396 | biological_process | RNA processing |
| D | 0042254 | biological_process | ribosome biogenesis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TAR A 401 |
| Chain | Residue |
| A | ASN15 |
| A | PHE16 |
| A | ARG17 |
| A | GLU48 |
| A | TYR97 |
| A | HOH420 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 410 |
| Chain | Residue |
| A | VAL245 |
| A | GLU247 |
| A | ARG253 |
| A | TRP134 |
| A | ARG191 |
| A | THR225 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE TAR B 401 |
| Chain | Residue |
| B | SER13 |
| B | ARG14 |
| B | ASN15 |
| B | ARG17 |
| B | HOH383 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 410 |
| Chain | Residue |
| B | TRP134 |
| B | THR225 |
| B | GLU247 |
| B | ARG253 |
| D | ARG146 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE TAR C 401 |
| Chain | Residue |
| C | SER13 |
| C | ASN15 |
| C | PHE16 |
| C | ARG17 |
| C | GLU48 |
| C | TYR97 |
| C | ARG319 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TAR D 401 |
| Chain | Residue |
| D | SER13 |
| D | ARG14 |
| D | ASN15 |
| D | PHE16 |
| D | ARG17 |
| D | TYR97 |
| D | ARG319 |
| D | HOH393 |
| D | HOH440 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE TAR D 402 |
| Chain | Residue |
| D | ARG198 |
| D | ARG230 |
| D | GLY231 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL D 410 |
| Chain | Residue |
| D | ARG191 |
| D | GLY192 |
| D | THR225 |
Functional Information from PROSITE/UniProt
| site_id | PS01287 |
| Number of Residues | 11 |
| Details | RTC RNA 3'-terminal phosphate cyclase signature. RGspPlGGGeV |
| Chain | Residue | Details |
| A | ARG155-VAL165 |
