3PPI
Crystal structure of 3-hydroxyacyl-CoA dehydrogenase type-2 from Mycobacterium avium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003857 | molecular_function | 3-hydroxyacyl-CoA dehydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047015 | molecular_function | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity |
| B | 0003857 | molecular_function | 3-hydroxyacyl-CoA dehydrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047015 | molecular_function | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity |
| C | 0003857 | molecular_function | 3-hydroxyacyl-CoA dehydrogenase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047015 | molecular_function | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity |
| D | 0003857 | molecular_function | 3-hydroxyacyl-CoA dehydrogenase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0047015 | molecular_function | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 300 |
| Chain | Residue |
| A | ALA49 |
| A | GLY53 |
| A | ALA56 |
| A | HOH712 |
| A | HOH714 |
| A | HOH715 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 301 |
| Chain | Residue |
| A | HOH286 |
| A | HOH868 |
| A | GLY15 |
| A | GLY18 |
| A | HOH270 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 300 |
| Chain | Residue |
| B | ALA49 |
| B | GLY53 |
| B | ALA56 |
| B | HOH477 |
| B | HOH643 |
| B | HOH644 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 301 |
| Chain | Residue |
| B | GLY15 |
| B | GLY18 |
| B | HOH307 |
| B | HOH323 |
| B | HOH329 |
| B | HOH427 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 300 |
| Chain | Residue |
| C | ALA49 |
| C | GLY53 |
| C | ALA56 |
| C | HOH260 |
| C | HOH781 |
| C | HOH825 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 301 |
| Chain | Residue |
| C | GLY15 |
| C | GLY18 |
| C | HOH419 |
| C | HOH671 |
| C | HOH673 |
| C | HOH775 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 300 |
| Chain | Residue |
| D | ALA49 |
| D | GLY53 |
| D | ALA56 |
| D | HOH689 |
| D | HOH690 |
| D | HOH691 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 301 |
| Chain | Residue |
| D | GLY15 |
| D | GLY18 |
| D | HOH679 |
| D | HOH681 |
| D | HOH682 |
| D | HOH860 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| A | GLY15 |
| A | ALA38 |
| A | ASP39 |
| A | THR61 |
| A | ASN62 |
| A | VAL63 |
| A | LEU117 |
| A | HOH870 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL C 302 |
| Chain | Residue |
| C | GLY15 |
| C | ALA38 |
| C | ASP39 |
| C | THR61 |
| C | ASN62 |
| C | VAL63 |
| C | HIS89 |
| C | LEU117 |
| C | HOH670 |
| C | HOH873 |
| site_id | BC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL D 302 |
| Chain | Residue |
| D | GLY15 |
| D | ALA38 |
| D | ASP39 |
| D | LEU40 |
| D | THR61 |
| D | ASN62 |
| D | VAL63 |
| D | LEU117 |
| D | HOH398 |
| D | HOH683 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SiagyegqigQtaYAAAKAGViGLTiAAA |
| Chain | Residue | Details |
| A | SER152-ALA180 |
