3PP5
High-resolution structure of the trimeric Scar/WAVE complex precursor Brk1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000281 | biological_process | mitotic cytokinesis |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005911 | cellular_component | cell-cell junction |
| A | 0007015 | biological_process | actin filament organization |
| A | 0008064 | biological_process | regulation of actin polymerization or depolymerization |
| A | 0031143 | cellular_component | pseudopodium |
| A | 0031209 | cellular_component | SCAR complex |
| A | 0031252 | cellular_component | cell leading edge |
| A | 0031269 | biological_process | pseudopodium assembly |
| A | 0032433 | cellular_component | filopodium tip |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0044877 | molecular_function | protein-containing complex binding |
| A | 0046847 | biological_process | filopodium assembly |
| A | 0048870 | biological_process | cell motility |
| A | 0060090 | molecular_function | molecular adaptor activity |
| A | 0060187 | cellular_component | cell pole |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD A 69 |
| Chain | Residue |
| A | TRP11 |
| A | LYS48 |
| A | ASP53 |
| A | HOH79 |
| A | HOH126 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MRD A 70 |
| Chain | Residue |
| A | PHE30 |
| A | ASN32 |
| A | HOH106 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 71 |
| Chain | Residue |
| A | GLU18 |
| A | ASP57 |
| A | HOH87 |
| A | HOH98 |
| A | HOH114 |
| A | GLU15 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 72 |
| Chain | Residue |
| A | GLU15 |
| A | GLU18 |
| A | ASP57 |
| A | GLU60 |
| A | HOH84 |
| A | HOH86 |
