Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3PND

FAD binding by ApbE protein from Salmonella enterica: a new class of FAD binding proteins

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0016740	molecular_function	transferase activity
A	0017013	biological_process	protein flavinylation
A	0046872	molecular_function	metal ion binding
B	0005886	cellular_component	plasma membrane
B	0016740	molecular_function	transferase activity
B	0017013	biological_process	protein flavinylation
B	0046872	molecular_function	metal ion binding
C	0005886	cellular_component	plasma membrane
C	0016740	molecular_function	transferase activity
C	0017013	biological_process	protein flavinylation
C	0046872	molecular_function	metal ion binding
D	0005886	cellular_component	plasma membrane
D	0016740	molecular_function	transferase activity
D	0017013	biological_process	protein flavinylation
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 357

Chain	Residue
A	SER99
A	GLU100
A	HOH427

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 358

Chain	Residue
A	GLY255
A	SER256
A	ASN259
A	SO4364
C	GLU37

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 359

Chain	Residue
A	GLY308
A	THR309
A	HIS282

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 360

Chain	Residue
A	TYR189
A	ASP192
A	ARG196
A	LEU295
A	HOH456

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 361

Chain	Residue
A	ASN283
A	LYS328
A	GLY330
C	ARG91

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 362

Chain	Residue
A	ARG267
A	HIS270
C	LYS39

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 363

Chain	Residue
A	HIS193
A	ARG196
A	HOH386
A	HOH392

site_id	AC8
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FAD A 500

Chain	Residue
A	MET41
A	THR43
A	ASP72
A	SER76
A	TYR78
A	ALA119
A	MET120
A	ASP121
A	VAL124
A	ASP181
A	SER183
A	THR184
A	GLU187
A	ARG267
A	HIS270
A	VAL271
A	ILE272
A	SO4364
A	HOH402
A	HOH562
C	LYS39

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 364

Chain	Residue
A	ARG267
A	SER269
A	HIS270
A	VAL271
A	SO4358
A	HOH371
A	FAD500

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 365

Chain	Residue
A	ARG317
A	TRP336
A	HOH411
C	GLN147

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 366

Chain	Residue
A	GLN310
A	GLU329
A	LYS334
C	ARG91
C	ASP177

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 367

Chain	Residue
A	GLN231
A	SER256
A	TYR257
A	ARG258

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 368

Chain	Residue
A	ARG217
B	ARG217
B	GLY218
B	ASN247
B	SO4366

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 369

Chain	Residue
A	ARG86
A	ARG278

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 357

Chain	Residue
B	SER90
B	ARG91
B	HOH521
B	HOH522

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 358

Chain	Residue
B	HIS89
D	ARG318

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 359

Chain	Residue
B	GLY255
B	ARG267
B	HOH423

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 360

Chain	Residue
B	LYS39
B	THR40
B	MET41
B	GLY42
B	HOH407

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 361

Chain	Residue
B	HIS282
B	ASN283
B	LEU284
B	GLY308
B	THR309

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 362

Chain	Residue
D	ARG318
D	GLU319
B	ARG91
B	PRO176
B	ASP177
B	HOH523
B	HOH528

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 363

Chain	Residue
B	TYR189
B	ASP192
B	ARG196
B	THR293
B	LEU295
B	HOH403

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 364

Chain	Residue
B	SER99
B	GLU100
B	GLN169
B	HOH413

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 365

Chain	Residue
B	SER256
B	ARG258
B	HOH408
D	ARG258

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 366

Chain	Residue
A	ARG217
A	GLY218
A	ASN247
A	SO4368
B	ARG217
B	HOH385

site_id	CC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE FAD B 500

Chain	Residue
B	HOH2
B	HOH4
B	MET41
B	THR43
B	ASP72
B	SER76
B	TYR78
B	ALA119
B	ASP121
B	VAL124
B	PHE133
B	ASP181
B	SER183
B	THR184
B	GLU187
B	HIS270
B	ILE272
B	HOH439
B	HOH557
D	LYS39

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 367

Chain	Residue
B	HIS193
B	ARG196
B	HOH375

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 368

Chain	Residue
B	ARG317
B	TRP336
B	HOH372

site_id	DC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 357

Chain	Residue
A	HOH6
A	ASP174
A	HOH399
C	ASN80
C	ASP81

site_id	DC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 358

Chain	Residue
B	ARG91
B	PRO176
B	HOH409
C	SER99
C	GLU100
C	HOH409

site_id	DC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 359

Chain	Residue
C	TYR189
C	ASP192
C	ARG196
C	LEU295
C	HOH414

site_id	DC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 360

Chain	Residue
A	LYS39
A	HOH426
C	PHE133
C	HIS270

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 361

Chain	Residue
C	GLY218
C	ASN247
C	HOH400
D	GLY218
D	ASN247

site_id	DC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 362

Chain	Residue
A	GLU37
C	SER256
C	SO4367
C	HOH418

site_id	DC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 363

Chain	Residue
C	HIS282
C	ASN283
C	LEU284
C	GLY308
C	THR309

site_id	DC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 364

Chain	Residue
C	PRO126
C	ASN129
C	TYR179
C	HOH377

site_id	DC9
Number of Residues	24
Details	BINDING SITE FOR RESIDUE FAD C 500

Chain	Residue
A	LYS39
C	HOH15
C	MET41
C	THR43
C	ASP72
C	SER76
C	TYR78
C	ALA119
C	MET120
C	ASP121
C	VAL124
C	ASP181
C	SER183
C	THR184
C	GLU187
C	ARG267
C	HIS270
C	VAL271
C	ILE272
C	SO4367
C	HOH373
C	HOH374
C	HOH390
C	HOH498

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 365

Chain	Residue
C	THR26
C	THR27
C	THR28
D	GLN172

site_id	EC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 366

Chain	Residue
A	GLN224
A	ARG227
C	ARG236
C	HOH559

site_id	EC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C 367

Chain	Residue
C	ARG267
C	SER269
C	HIS270
C	VAL271
C	SO4362
C	HOH392
C	FAD500

site_id	EC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 357

Chain	Residue
D	SER99
D	GLU100
D	GLN169

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 358

Chain	Residue
D	ARG165
D	ALA166
D	HIS168

site_id	EC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 359

Chain	Residue
B	GLU37
D	GLY255
D	ARG267
D	HOH381
D	HOH388
D	HOH429

site_id	EC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 360

Chain	Residue
D	HIS282
D	ASN283
D	LEU284
D	GLY308
D	THR309

site_id	EC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 361

Chain	Residue
B	ARG258
D	GLN231
D	SER256
D	TYR257
D	ARG258

site_id	EC9
Number of Residues	25
Details	BINDING SITE FOR RESIDUE FAD D 500

Chain	Residue
B	LYS39
D	MET41
D	GLY42
D	THR43
D	ASP72
D	SER76
D	TYR78
D	ALA119
D	MET120
D	ASP121
D	VAL124
D	VAL128
D	PHE133
D	ASP181
D	SER183
D	THR184
D	GLU187
D	ARG267
D	HIS270
D	VAL271
D	ILE272
D	HOH368
D	HOH396
D	HOH401
D	HOH513

site_id	FC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 362

Chain	Residue
B	GLY330
B	GLU331
D	SER90
D	ARG91
D	SER92

site_id	FC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 363

Chain	Residue
D	GLN158
D	HIS159

site_id	FC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 364

Chain	Residue
B	TYR261
D	GLN224
D	ARG227

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269\|PubMed:21148731

Chain	Residue	Details
A	MET41
B	ASP181
B	GLU187
B	ILE272
C	MET41
C	TYR78
C	ALA119
C	ASP181
C	GLU187
C	ILE272
D	MET41
A	TYR78
D	TYR78
D	ALA119
D	ASP181
D	GLU187
D	ILE272
A	ALA119
A	ASP181
A	GLU187
A	ILE272
B	MET41
B	TYR78
B	ALA119

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P0AB85

Chain	Residue	Details
A	THR184
A	ASP301
B	THR184
B	ASP301
C	THR184
C	ASP301
D	THR184
D	ASP301

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:O83774

Chain	Residue	Details
A	ASP298
A	THR302
B	ASP298
B	THR302
C	ASP298
C	THR302
D	ASP298
D	THR302

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)