3PN8
The crystal structure of 6-phospho-beta-glucosidase from Streptococcus mutans UA159
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008422 | molecular_function | beta-glucosidase activity |
| A | 0008706 | molecular_function | 6-phospho-beta-glucosidase activity |
| A | 0016052 | biological_process | carbohydrate catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008422 | molecular_function | beta-glucosidase activity |
| B | 0008706 | molecular_function | 6-phospho-beta-glucosidase activity |
| B | 0016052 | biological_process | carbohydrate catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 478 |
| Chain | Residue |
| A | TRP349 |
| A | SER430 |
| A | ALA431 |
| A | GLY432 |
| A | LYS438 |
| A | TYR440 |
| A | HOH620 |
| A | HOH654 |
| A | HOH689 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 479 |
| Chain | Residue |
| A | ARG437 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 480 |
| Chain | Residue |
| A | PHE292 |
| A | THR293 |
| A | GLU294 |
| A | LYS297 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 481 |
| Chain | Residue |
| A | ASN249 |
| A | LYS251 |
| A | HOH617 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 482 |
| Chain | Residue |
| A | LYS251 |
| A | TYR328 |
| A | HOH748 |
| A | HOH772 |
| B | HOH676 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 483 |
| Chain | Residue |
| A | ARG147 |
| A | ASP151 |
| A | ARG220 |
| A | ARG295 |
| A | HOH758 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 484 |
| Chain | Residue |
| A | ARG162 |
| A | LYS165 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 485 |
| Chain | Residue |
| A | ASN7 |
| A | LEU417 |
| A | MSE418 |
| A | HOH537 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 486 |
| Chain | Residue |
| A | THR247 |
| A | VAL337 |
| A | LYS338 |
| A | HOH594 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 487 |
| Chain | Residue |
| A | MSE314 |
| A | HOH515 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 488 |
| Chain | Residue |
| A | LYS281 |
| A | ARG285 |
| A | TYR327 |
| B | ASP411 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 489 |
| Chain | Residue |
| A | PRO102 |
| A | ASN103 |
| A | GLU104 |
| A | ALA105 |
| A | HOH500 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG A 490 |
| Chain | Residue |
| A | LYS338 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT A 491 |
| Chain | Residue |
| A | GLU25 |
| A | GLY26 |
| A | LYS28 |
| A | ARG92 |
| A | ASN103 |
| A | GLY106 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 492 |
| Chain | Residue |
| A | PHE301 |
| A | THR304 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT A 493 |
| Chain | Residue |
| A | TYR66 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT A 494 |
| Chain | Residue |
| A | LYS338 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 495 |
| Chain | Residue |
| A | ASP397 |
| A | LYS404 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT A 496 |
| Chain | Residue |
| A | TYR394 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 497 |
| Chain | Residue |
| A | ARG322 |
| A | GLU323 |
| site_id | CC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 B 478 |
| Chain | Residue |
| B | TRP349 |
| B | SER430 |
| B | ALA431 |
| B | GLY432 |
| B | LYS438 |
| B | TYR440 |
| B | HOH558 |
| B | HOH605 |
| B | HOH702 |
| B | HOH743 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 479 |
| Chain | Residue |
| B | ARG295 |
| B | LYS298 |
| B | HOH540 |
| site_id | CC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 480 |
| Chain | Residue |
| B | ARG437 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 481 |
| Chain | Residue |
| B | PHE292 |
| B | GLU294 |
| B | LYS297 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 482 |
| Chain | Residue |
| B | ASN7 |
| B | LEU417 |
| B | MSE418 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG B 483 |
| Chain | Residue |
| B | ASP348 |
| B | TRP349 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 484 |
| Chain | Residue |
| B | PHE301 |
| B | THR304 |
| B | HOH491 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 485 |
| Chain | Residue |
| B | ALA344 |
| B | PHE378 |
| B | HOH670 |
| B | HOH711 |
| B | HOH735 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 486 |
| Chain | Residue |
| B | PHE81 |
| B | LYS82 |
| B | TYR120 |
| B | GLY121 |
| B | HOH684 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B 487 |
| Chain | Residue |
| B | GLY42 |
| B | VAL43 |
| B | THR433 |
| B | HOH559 |
| site_id | DC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT B 488 |
| Chain | Residue |
| B | PRO340 |
| site_id | DC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT B 489 |
| Chain | Residue |
| B | ASP346 |
Functional Information from PROSITE/UniProt
| site_id | PS00572 |
| Number of Residues | 9 |
| Details | GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. LFIVENGFG |
| Chain | Residue | Details |
| A | LEU371-GLY379 |
| site_id | PS00653 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FlWGgAvAAHQlEgG |
| Chain | Residue | Details |
| A | PHE8-GLY22 |
