3PM6

Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004332	molecular_function	fructose-bisphosphate aldolase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0006096	biological_process	glycolytic process
A	0008270	molecular_function	zinc ion binding
A	0016829	molecular_function	lyase activity
A	0016832	molecular_function	aldehyde-lyase activity
A	0046872	molecular_function	metal ion binding
B	0004332	molecular_function	fructose-bisphosphate aldolase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0006096	biological_process	glycolytic process
B	0008270	molecular_function	zinc ion binding
B	0016829	molecular_function	lyase activity
B	0016832	molecular_function	aldehyde-lyase activity
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 304

Chain	Residue
B	THR20

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 306

Chain	Residue
B	TRP57
B	HOH339

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 307

Chain	Residue
B	GLN89

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 308

Chain	Residue
B	ARG96

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 309

Chain	Residue
B	LYS95
B	HOH357

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 303

Chain	Residue
A	GLN89

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 304

Chain	Residue
A	ILE93

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 305

Chain	Residue
A	ARG96

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 306

Chain	Residue
A	LYS95
A	GLU131
A	IOD307

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 307

Chain	Residue
A	GLU131
A	IOD306

---

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 309

Chain	Residue
A	ARG239

---

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 310

Chain	Residue
A	TYR204

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 311

Chain	Residue
A	TYR195

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 314

Chain	Residue
A	LYS261

---

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 315

Chain	Residue
A	HIS21

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 316

Chain	Residue
A	HOH458

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 311

Chain	Residue
B	ASN252
B	HOH370

---

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 313

Chain	Residue
A	ASN194

---

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 314

Chain	Residue
B	HIS21

---

site_id	CC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 315

Chain	Residue
B	HOH398

---

site_id	CC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 318

Chain	Residue
A	GLU164

---

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 318

Chain	Residue
B	ILE93

---

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 319

Chain	Residue
B	LYS95
B	HOH394

---

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 319

Chain	Residue
A	HIS87
A	HIS192
A	HIS223

---

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 320

Chain	Residue
B	HIS87
B	HIS223
B	HOH400
B	HOH402
B	HOH403

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000250

Chain	Residue	Details
A	ASP86
B	ASP86

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	HIS87
B	ASP116
B	GLU146
B	HIS192
B	GLY193
B	HIS223
B	GLY224
B	ASN245
A	ASP116
A	GLU146
A	HIS192
A	GLY193
A	HIS223
A	GLY224
A	ASN245
B	HIS87

---