Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3PKP

Q83S Variant of S. Enterica RmlA with dATP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000271	biological_process	polysaccharide biosynthetic process
A	0000287	molecular_function	magnesium ion binding
A	0005829	cellular_component	cytosol
A	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
A	0009058	biological_process	biosynthetic process
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0009243	biological_process	O antigen biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019305	biological_process	dTDP-rhamnose biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0000271	biological_process	polysaccharide biosynthetic process
B	0000287	molecular_function	magnesium ion binding
B	0005829	cellular_component	cytosol
B	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
B	0009058	biological_process	biosynthetic process
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0009243	biological_process	O antigen biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019305	biological_process	dTDP-rhamnose biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0000271	biological_process	polysaccharide biosynthetic process
C	0000287	molecular_function	magnesium ion binding
C	0005829	cellular_component	cytosol
C	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
C	0009058	biological_process	biosynthetic process
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0009243	biological_process	O antigen biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0019305	biological_process	dTDP-rhamnose biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0000271	biological_process	polysaccharide biosynthetic process
D	0000287	molecular_function	magnesium ion binding
D	0005829	cellular_component	cytosol
D	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
D	0009058	biological_process	biosynthetic process
D	0009103	biological_process	lipopolysaccharide biosynthetic process
D	0009243	biological_process	O antigen biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0019305	biological_process	dTDP-rhamnose biosynthetic process
D	0046872	molecular_function	metal ion binding
I	0000271	biological_process	polysaccharide biosynthetic process
I	0000287	molecular_function	magnesium ion binding
I	0005829	cellular_component	cytosol
I	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
I	0009058	biological_process	biosynthetic process
I	0009103	biological_process	lipopolysaccharide biosynthetic process
I	0009243	biological_process	O antigen biosynthetic process
I	0016740	molecular_function	transferase activity
I	0016779	molecular_function	nucleotidyltransferase activity
I	0019305	biological_process	dTDP-rhamnose biosynthetic process
I	0046872	molecular_function	metal ion binding
J	0000271	biological_process	polysaccharide biosynthetic process
J	0000287	molecular_function	magnesium ion binding
J	0005829	cellular_component	cytosol
J	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
J	0009058	biological_process	biosynthetic process
J	0009103	biological_process	lipopolysaccharide biosynthetic process
J	0009243	biological_process	O antigen biosynthetic process
J	0016740	molecular_function	transferase activity
J	0016779	molecular_function	nucleotidyltransferase activity
J	0019305	biological_process	dTDP-rhamnose biosynthetic process
J	0046872	molecular_function	metal ion binding
K	0000271	biological_process	polysaccharide biosynthetic process
K	0000287	molecular_function	magnesium ion binding
K	0005829	cellular_component	cytosol
K	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
K	0009058	biological_process	biosynthetic process
K	0009103	biological_process	lipopolysaccharide biosynthetic process
K	0009243	biological_process	O antigen biosynthetic process
K	0016740	molecular_function	transferase activity
K	0016779	molecular_function	nucleotidyltransferase activity
K	0019305	biological_process	dTDP-rhamnose biosynthetic process
K	0046872	molecular_function	metal ion binding
L	0000271	biological_process	polysaccharide biosynthetic process
L	0000287	molecular_function	magnesium ion binding
L	0005829	cellular_component	cytosol
L	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
L	0009058	biological_process	biosynthetic process
L	0009103	biological_process	lipopolysaccharide biosynthetic process
L	0009243	biological_process	O antigen biosynthetic process
L	0016740	molecular_function	transferase activity
L	0016779	molecular_function	nucleotidyltransferase activity
L	0019305	biological_process	dTDP-rhamnose biosynthetic process
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE DTP A 500

Chain	Residue
A	LEU9
A	GLN27
A	SER83
A	SER85
A	PRO86
A	GLY110
A	ASP111
A	MG501
A	MG502
A	ALA10
A	GLY11
A	GLY12
A	SER13
A	GLY14
A	THR15
A	ARG16
A	LYS26

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	ARG16
A	ASP111
A	ASP226
A	DTP500

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 502

Chain	Residue
A	DTP500

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DTP B 500

Chain	Residue
B	LEU9
B	GLY11
B	GLY12
B	SER13
B	GLY14
B	THR15
B	ARG16
B	LYS26
B	GLN27
B	SER83
B	SER85
B	PRO86
B	GLY110
B	ASP111
B	MG501
B	MG502

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 501

Chain	Residue
B	ARG16
B	ASP111
B	ASP226
B	DTP500

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG B 502

Chain	Residue
B	DTP500

site_id	AC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE DTP C 500

Chain	Residue
C	LEU9
C	GLY11
C	GLY12
C	SER13
C	GLY14
C	THR15
C	ARG16
C	LYS26
C	GLN27
C	SER83
C	SER85
C	PRO86
C	GLY110
C	ASP111
C	MG501
C	MG502
D	LYS278

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 501

Chain	Residue
C	ARG16
C	ASP111
C	ASP226
C	DTP500

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 502

Chain	Residue
C	DTP500

site_id	BC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DTP D 500

Chain	Residue
D	LEU9
D	GLY11
D	GLY12
D	SER13
D	GLY14
D	THR15
D	ARG16
D	LYS26
D	GLN27
D	SER83
D	SER85
D	PRO86
D	GLY110
D	ASP111
D	MG501
D	MG502

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 501

Chain	Residue
D	ASP111
D	ASP226
D	DTP500

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 502

Chain	Residue
D	DTP500

site_id	BC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE DTP I 500

Chain	Residue
I	MG501
I	MG502
J	HOH313
I	LEU9
I	GLY11
I	GLY12
I	SER13
I	GLY14
I	THR15
I	ARG16
I	LYS26
I	GLN27
I	SER83
I	SER85
I	PRO86
I	GLY110
I	ASP111

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG I 501

Chain	Residue
I	ASP111
I	ASP226
I	HOH313
I	DTP500

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG I 502

Chain	Residue
I	DTP500

site_id	BC7
Number of Residues	18
Details	BINDING SITE FOR RESIDUE DTP J 500

Chain	Residue
J	LEU9
J	ALA10
J	GLY11
J	GLY12
J	SER13
J	GLY14
J	THR15
J	ARG16
J	LYS26
J	GLN27
J	SER83
J	SER85
J	PRO86
J	GLY110
J	ASP111
J	HOH304
J	MG501
J	MG502

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG J 501

Chain	Residue
J	ASP111
J	ASP226
J	DTP500

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG J 502

Chain	Residue
J	DTP500

site_id	CC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE DTP K 500

Chain	Residue
K	GLY11
K	GLY12
K	SER13
K	GLY14
K	THR15
K	ARG16
K	LYS26
K	GLN27
K	SER83
K	SER85
K	PRO86
K	GLY110
K	ASP111
K	MG501
K	MG502

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG K 501

Chain	Residue
K	ARG16
K	ASP111
K	ASP226
K	DTP500

site_id	CC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG K 502

Chain	Residue
K	DTP500

site_id	CC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DTP L 500

Chain	Residue
L	LEU9
L	GLY11
L	GLY12
L	SER13
L	GLY14
L	THR15
L	ARG16
L	LYS26
L	GLN27
L	SER83
L	SER85
L	PRO86
L	GLY110
L	ASP111
L	MG501
L	MG502

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG L 501

Chain	Residue
L	ARG16
L	ASP111
L	ASP226
L	DTP500

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG L 502

Chain	Residue
L	DTP500

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P61887","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)