Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 428 |
| Chain | Residue |
| A | HIS423 |
| A | HIS425 |
| B | ASP53 |
| B | HOH477 |
| B | HOH534 |
| B | HOH649 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE C8E A 429 |
| Chain | Residue |
| A | TYR250 |
| B | C8E435 |
| A | THR187 |
| A | ASN244 |
| A | ALA246 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE C8E A 430 |
| Chain | Residue |
| A | VAL387 |
| A | TRP411 |
| B | PHE421 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE LDA A 431 |
| Chain | Residue |
| A | GLN169 |
| A | GLN180 |
| B | GLN180 |
| B | C8E435 |
| B | HOH640 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE LDA A 432 |
| Chain | Residue |
| A | TRP209 |
| A | TYR227 |
| A | TRP275 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE LDA A 433 |
| Chain | Residue |
| A | GLN180 |
| B | ILE170 |
| B | C8E435 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE LDA A 434 |
| Chain | Residue |
| A | GLY48 |
| A | MET82 |
| B | HOH599 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE LDA A 436 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE LDA A 437 |
| Chain | Residue |
| A | GLY132 |
| A | ALA133 |
| site_id | BC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE C8E A 438 |
| Chain | Residue |
| A | ALA153 |
| A | ILE155 |
| A | ASN201 |
| A | PHE235 |
| A | ASN238 |
| A | TYR239 |
| A | GLY265 |
| A | LEU269 |
| A | ASN270 |
| A | TRP298 |
| A | PHE301 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE C8E A 439 |
| Chain | Residue |
| A | ALA77 |
| A | PRO80 |
| A | SER100 |
| A | GLY103 |
| A | LEU123 |
| A | THR125 |
| A | ARG366 |
| A | MET390 |
| A | ALA410 |
| A | HOH583 |
| A | HOH662 |
| A | HOH783 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 1428 |
| Chain | Residue |
| A | GLN4 |
| A | ASN6 |
| A | GLU7 |
| A | TRP368 |
| A | HOH772 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE C8E A 440 |
| Chain | Residue |
| A | LEU162 |
| A | GLY163 |
| A | GLN169 |
| A | ILE191 |
| A | C8E442 |
| A | HOH775 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE C8E A 441 |
| Chain | Residue |
| A | ASP336 |
| A | TRP339 |
| A | VAL383 |
| B | PHE207 |
| B | LDA429 |
| B | HOH550 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE C8E A 442 |
| Chain | Residue |
| A | VAL166 |
| A | GLN169 |
| A | PRO401 |
| A | C8E440 |
| A | C8E443 |
| A | HOH707 |
| B | GLY251 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE C8E A 443 |
| Chain | Residue |
| A | GLY251 |
| A | C8E442 |
| B | VAL166 |
| B | GLN169 |
| B | C8E435 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE LDA B 429 |
| Chain | Residue |
| A | C8E441 |
| B | ALA96 |
| B | ILE98 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE LDA B 430 |
| Chain | Residue |
| B | LEU225 |
| B | TYR227 |
| B | TRP275 |
| site_id | CC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE C8E B 431 |
| Chain | Residue |
| B | ASN270 |
| B | LEU271 |
| B | TRP298 |
| B | PHE301 |
| B | ALA306 |
| B | ILE361 |
| B | GLY2 |
| B | ALA153 |
| B | LEU200 |
| B | ASN201 |
| B | GLY202 |
| B | PHE235 |
| B | GLY237 |
| B | ASN238 |
| B | GLY265 |
| B | LEU269 |
| site_id | CC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE C8E B 432 |
| Chain | Residue |
| B | ILE52 |
| B | ALA77 |
| B | TRP78 |
| B | PRO80 |
| B | SER100 |
| B | LEU104 |
| B | THR125 |
| B | MET126 |
| B | LYS409 |
| B | ALA410 |
| B | HOH451 |
| B | HOH619 |
| B | HOH756 |
| B | ACT1428 |
| site_id | CC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE C8E B 433 |
| Chain | Residue |
| A | ALA49 |
| A | TRP78 |
| A | VAL385 |
| A | PHE413 |
| A | GLY414 |
| A | THR415 |
| B | PHE92 |
| B | GLY93 |
| B | TRP94 |
| B | GLY132 |
| B | ALA133 |
| B | HOH599 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 1428 |
| Chain | Residue |
| B | GLN4 |
| B | ASN6 |
| B | GLU7 |
| B | ARG366 |
| B | TRP368 |
| B | C8E432 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE C8E B 434 |
| Chain | Residue |
| B | GLN169 |
| B | ILE191 |
| B | LEU243 |
| B | PHE247 |
| B | HOH488 |
| B | HOH624 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE C8E B 435 |
| Chain | Residue |
| A | C8E429 |
| A | LDA431 |
| A | LDA433 |
| A | C8E443 |
| B | THR187 |
| B | ASN244 |
| B | PHE247 |
| B | HOH734 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2PE B 436 |
| Chain | Residue |
| B | ASP218 |
| B | ASN221 |
| B | VAL277 |
| B | ASN281 |
| B | ILE289 |
| B | TYR291 |
| B | ILE327 |
