3PGL
Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1 |
| Chain | Residue |
| A | HOH2 |
| A | HOH32 |
| A | ASP96 |
| A | ASP98 |
| A | ASN207 |
| A | HOH258 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE RZX A 257 |
| Chain | Residue |
| A | TYR158 |
| A | ARG178 |
| A | TYR188 |
| A | HOH21 |
| A | HOH39 |
| A | VAL118 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1 |
| Chain | Residue |
| B | HOH2 |
| B | HOH4 |
| B | HOH66 |
| B | ASP96 |
| B | ASP98 |
| B | ASN207 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 316 |
| Details | Domain: {"description":"FCP1 homology","evidences":[{"source":"PROSITE-ProRule","id":"PRU00336","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"4-aspartylphosphate intermediate","evidences":[{"source":"PubMed","id":"15304220","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17157258","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"15304220","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15304220","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"15304220","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
