Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3PG9

Thermotoga maritima DAH7P synthase in complex with inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009058	biological_process	biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016832	molecular_function	aldehyde-lyase activity
B	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009058	biological_process	biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016832	molecular_function	aldehyde-lyase activity
C	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009058	biological_process	biosynthetic process
C	0009073	biological_process	aromatic amino acid family biosynthetic process
C	0009423	biological_process	chorismate biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016832	molecular_function	aldehyde-lyase activity
D	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009058	biological_process	biosynthetic process
D	0009073	biological_process	aromatic amino acid family biosynthetic process
D	0009423	biological_process	chorismate biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016832	molecular_function	aldehyde-lyase activity
E	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
E	0008652	biological_process	amino acid biosynthetic process
E	0009058	biological_process	biosynthetic process
E	0009073	biological_process	aromatic amino acid family biosynthetic process
E	0009423	biological_process	chorismate biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016832	molecular_function	aldehyde-lyase activity
F	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
F	0008652	biological_process	amino acid biosynthetic process
F	0009058	biological_process	biosynthetic process
F	0009073	biological_process	aromatic amino acid family biosynthetic process
F	0009423	biological_process	chorismate biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016832	molecular_function	aldehyde-lyase activity
G	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
G	0008652	biological_process	amino acid biosynthetic process
G	0009058	biological_process	biosynthetic process
G	0009073	biological_process	aromatic amino acid family biosynthetic process
G	0009423	biological_process	chorismate biosynthetic process
G	0016740	molecular_function	transferase activity
G	0016832	molecular_function	aldehyde-lyase activity
H	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
H	0008652	biological_process	amino acid biosynthetic process
H	0009058	biological_process	biosynthetic process
H	0009073	biological_process	aromatic amino acid family biosynthetic process
H	0009423	biological_process	chorismate biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016832	molecular_function	aldehyde-lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TYR A 339

Chain	Residue
A	SER31
F	ILE41
F	ILE42
F	GLY43
A	GLY33
A	GLN34
A	GLU35
A	ARG36
A	VAL38
F	MET1
F	ILE2
F	GLY40

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE TYR A 340

Chain	Residue
A	MET1
A	ILE2
A	GLY40
A	ILE41
A	ILE42
A	GLY43
A	ASP45
A	VAL65
A	HOH356
F	SER31
F	GLY33
F	GLN34
F	GLU35
F	ARG36
F	VAL38

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE AZI A 341

Chain	Residue
A	ARG285
A	GLU321

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NO3 A 342

Chain	Residue
A	PHE210
A	MET211
F	PHE242
G	PHE210
G	MET211

site_id	AC5
Number of Residues	13
Details	BINDING SITE FOR RESIDUE TYR B 339

Chain	Residue
B	MET1
B	ILE2
B	GLY40
B	ILE41
B	ILE42
B	GLY43
B	ASP45
G	SER31
G	GLY33
G	GLN34
G	GLU35
G	ARG36
G	VAL38

site_id	AC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TYR B 340

Chain	Residue
B	SER31
B	GLY33
B	GLN34
B	GLU35
B	ARG36
G	MET1
G	ILE2
G	GLY40
G	ILE41
G	ILE42
G	GLY43
G	ASP45

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE AZI B 341

Chain	Residue
B	PHE76

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 342

Chain	Residue
B	LYS207
B	ARG237

site_id	AC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE TYR C 339

Chain	Residue
C	MET1
C	ILE2
C	GLY40
C	ILE41
C	ILE42
C	GLY43
C	ASP45
C	VAL65
E	SER31
E	GLY33
E	GLN34
E	GLU35
E	ARG36
E	VAL38

site_id	BC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TYR C 340

Chain	Residue
C	SER31
C	GLY33
C	GLN34
C	GLU35
C	ARG36
C	VAL38
E	MET1
E	ILE41
E	ILE42
E	GLY43
E	LEU66

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NO3 C 341

Chain	Residue
C	PHE210
C	MET211
D	PHE242
E	PHE242
H	PHE210
H	MET211

site_id	BC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE TYR D 339

Chain	Residue
H	MET1
H	ILE2
H	GLY40
H	ILE41
H	ILE42
H	GLY43
H	ASP45
H	LEU66
D	SER31
D	GLY33
D	GLN34
D	GLU35
D	ARG36
D	VAL38

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NO3 D 340

Chain	Residue
C	PHE242
D	PHE210
D	MET211
D	ARG240
E	PHE210
E	MET211

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO3 F 339

Chain	Residue
A	PHE242
B	PHE210
B	MET211
F	PHE210
F	MET211
F	ARG240
G	PHE242

site_id	BC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE TYR H 339

Chain	Residue
D	MET1
D	ILE2
D	GLY40
D	ILE41
D	ILE42
D	GLY43
D	ASP45
D	HOH375
H	SER31
H	GLY33
H	GLN34
H	GLU35
H	ARG36
H	VAL38

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)