3PFY
The catalytic domain of human OTUD5
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PEG A 400 |
| Chain | Residue |
| A | ASP238 |
| A | HOH460 |
| A | GLU241 |
| A | GLU241 |
| A | VAL242 |
| A | VAL242 |
| A | HOH404 |
| A | HOH404 |
| A | HOH417 |
| A | HOH460 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 401 |
| Chain | Residue |
| A | LYS216 |
| A | ASP231 |
| A | GLN232 |
| A | GLY235 |
| A | VAL334 |
| A | HOH439 |
| A | HOH447 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG4 A 402 |
| Chain | Residue |
| A | GLU197 |
| A | GLN199 |
| A | TRP202 |
| A | TYR257 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | LYS219 |
| A | ARG227 |
| A | HOH449 |
| A | HOH484 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255 |
| Chain | Residue | Details |
| A | ASP221 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:22245969, ECO:0000269|PubMed:33110214 |
| Chain | Residue | Details |
| A | CYS224 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:22245969 |
| Chain | Residue | Details |
| A | VAL334 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:22245969 |
| Chain | Residue | Details |
| A | TYR175 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:22245969, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER177 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:33110214 |
| Chain | Residue | Details |
| A | THR195 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by MTOR => ECO:0000269|PubMed:33110214 |
| Chain | Residue | Details |
| A | ILE328 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:33110214 |
| Chain | Residue | Details |
| A | ASN337 |
