3PFE

Crystal structure of a M20A metallo peptidase (dapE, lpg0809) from Legionella pneumophila subsp. pneumophila str. philadelphia 1 at 1.50 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	HIS96
A	ASP129
A	GLU162
A	ASP190
A	ZN502
A	HOH926

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 502

Chain	Residue
A	ZN501
A	GOL518
A	HOH926
A	ASP129
A	GLU163
A	HIS442

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 503

Chain	Residue
A	HIS52
A	ASP264
A	CL507
A	CL508

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 504

Chain	Residue
A	GLU410
A	CL505
A	IMD513
A	HOH1002

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL A 505

Chain	Residue
A	SER226
A	ARG305
A	GLU410
A	GLY411
A	ZN504
A	IMD513
A	HOH941

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 506

Chain	Residue
A	SER224
A	ASN327
A	VAL328
A	HIS442
A	HOH692

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 507

Chain	Residue
A	HIS52
A	ASP264
A	ZN503

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 508

Chain	Residue
A	GLN48
A	HIS52
A	ASP264
A	ZN503

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 509

Chain	Residue
A	PHE424
A	PRO425
A	LYS426
A	HOH681

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 510

Chain	Residue
A	HIS223
A	ARG340
A	THR413
A	HOH692

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 511

Chain	Residue
A	GLY105
A	TRP106
A	HOH823
A	HOH890

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 512

Chain	Residue
A	ASP37
A	ALA38

---

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IMD A 513

Chain	Residue
A	HIS223
A	SER226
A	GLU410
A	LEU435
A	ZN504
A	CL505
A	GOL518
A	HOH555

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PEG A 514

Chain	Residue
A	GLN269
A	GLN272
A	TYR407
A	HOH601
A	HOH627

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 515

Chain	Residue
A	GLN240
A	ASN249
A	PRO363
A	TYR364
A	HOH712

---

site_id	BC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 516

Chain	Residue
A	THR250
A	GLY251
A	GLU252
A	ASN304
A	ARG308
A	HOH540
A	HOH580
A	HOH666
A	HOH1034

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 517

Chain	Residue
A	LYS58
A	GLU68
A	ILE69
A	HOH664
A	HOH998

---

site_id	BC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A 518

Chain	Residue
A	ASP190
A	HIS223
A	GLU410
A	GLY412
A	ILE414
A	LEU435
A	HIS442
A	ZN502
A	IMD513
A	HOH768
A	HOH926

---

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 519

Chain	Residue
A	GLN423
A	HOH545
A	HOH788
A	LYS177
A	GLU178
A	GLY181

---

site_id	CC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 520

Chain	Residue
A	GLY165
A	SER166
A	GLY375
A	GLY376
A	SER377
A	HOH613
A	HOH714
A	HOH964

---

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 521

Chain	Residue
A	SER107
A	LEU110
A	LYS118

---

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 522

Chain	Residue
A	HIS438
A	HIS449
A	HOH706
A	HOH833
A	HOH868

---

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 523

Chain	Residue
A	HIS35
A	SER164
A	TYR167
A	HOH835

---

site_id	CC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 524

Chain	Residue
A	GLU41
A	GLU42
A	TYR259
A	CYS260
A	ASP261
A	HOH910
A	HOH991

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