Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3PEO

Crystal structure of acetylcholine binding protein complexed with metocurine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CU9 A 301

Chain	Residue
A	GLN57
E	CYS190
A	MET116
A	ILE118
A	SER167
A	HOH562
A	HOH1158
E	TYR93
E	TRP147
E	TYR188

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE CU9 B 301

Chain	Residue
A	TYR93
A	SER146
A	TRP147
A	TYR188
A	CYS191
A	TYR195
B	THR36
B	GLN38
B	TYR55
B	GLN57
B	SER166
B	SER167
B	HOH245
B	HOH384
I	ASP161

site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE CU9 C 301

Chain	Residue
C	TYR93
C	SER146
C	TRP147
C	TYR188
C	TYR195
C	HOH1245
D	THR36
D	GLN38
D	TYR55
D	GLN57
D	SER166
D	SER167
D	HOH508

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CU9 D 301

Chain	Residue
D	TYR93
D	LYS143
D	SER146
D	TRP147
D	TYR188
D	HOH556
E	THR36
E	TYR55
E	SER166
E	SER167
E	HOH849

site_id	AC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE CU9 F 301

Chain	Residue
D	ASP161
F	TYR93
F	LYS143
F	SER146
F	TRP147
F	TYR188
F	CYS191
F	TYR195
F	HOH237
F	HOH315
G	THR36
G	GLN38
G	TYR55
G	GLN57
G	SER166
G	SER167

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CU9 F 220

Chain	Residue
F	MET116
F	ILE118
F	SER167
F	HOH517
F	HOH822
F	HOH1276
J	TYR93
J	SER146
J	TRP147
J	TYR188
J	CYS190

site_id	AC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE CU9 H 301

Chain	Residue
H	TYR93
H	LYS143
H	SER146
H	TRP147
H	TYR188
H	TYR195
H	HOH1228
I	THR36
I	GLN38
I	TYR55
I	GLN57
I	SER166
I	SER167
I	HOH332

site_id	AC8
Number of Residues	13
Details	BINDING SITE FOR RESIDUE CU9 J 301

Chain	Residue
J	GLN57
J	SER166
J	SER167
J	HOH929
I	TYR93
I	LYS143
I	SER146
I	TRP147
I	TYR188
I	HOH469
J	THR36
J	GLN38
J	TYR55

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)