3PCR

Structure of EspG-Arf6 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
B	0000166	molecular_function	nucleotide binding
B	0001726	cellular_component	ruffle
B	0003924	molecular_function	GTPase activity
B	0003925	molecular_function	G protein activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005768	cellular_component	endosome
B	0005769	cellular_component	early endosome
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005925	cellular_component	focal adhesion
B	0005938	cellular_component	cell cortex
B	0006886	biological_process	intracellular protein transport
B	0007155	biological_process	cell adhesion
B	0007399	biological_process	nervous system development
B	0010008	cellular_component	endosome membrane
B	0010975	biological_process	regulation of neuron projection development
B	0010976	biological_process	positive regulation of neuron projection development
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0016192	biological_process	vesicle-mediated transport
B	0016787	molecular_function	hydrolase activity
B	0019003	molecular_function	GDP binding
B	0030139	cellular_component	endocytic vesicle
B	0030154	biological_process	cell differentiation
B	0030496	cellular_component	midbody
B	0030838	biological_process	positive regulation of actin filament polymerization
B	0030866	biological_process	cortical actin cytoskeleton organization
B	0031527	cellular_component	filopodium membrane
B	0031901	cellular_component	early endosome membrane
B	0031996	molecular_function	thioesterase binding
B	0032154	cellular_component	cleavage furrow
B	0032456	biological_process	endocytic recycling
B	0034394	biological_process	protein localization to cell surface
B	0035020	biological_process	regulation of Rac protein signal transduction
B	0035591	molecular_function	signaling adaptor activity
B	0036010	biological_process	protein localization to endosome
B	0048261	biological_process	negative regulation of receptor-mediated endocytosis
B	0048488	biological_process	synaptic vesicle endocytosis
B	0050714	biological_process	positive regulation of protein secretion
B	0051301	biological_process	cell division
B	0051489	biological_process	regulation of filopodium assembly
B	0051549	biological_process	positive regulation of keratinocyte migration
B	0055037	cellular_component	recycling endosome
B	0055038	cellular_component	recycling endosome membrane
B	0060998	biological_process	regulation of dendritic spine development
B	0070062	cellular_component	extracellular exosome
B	0072659	biological_process	protein localization to plasma membrane
B	0090543	cellular_component	Flemming body
B	0097178	biological_process	ruffle assembly
B	0098793	cellular_component	presynapse
B	0098794	cellular_component	postsynapse
B	0098978	cellular_component	glutamatergic synapse
B	0099562	biological_process	maintenance of postsynaptic density structure
B	0120183	biological_process	positive regulation of focal adhesion disassembly
B	1903078	biological_process	positive regulation of protein localization to plasma membrane
B	1903438	biological_process	positive regulation of mitotic cytokinetic process
B	1905345	biological_process	protein localization to cleavage furrow
B	1905606	biological_process	regulation of presynapse assembly
B	1990090	biological_process	cellular response to nerve growth factor stimulus
B	2000009	biological_process	negative regulation of protein localization to cell surface
B	2000171	biological_process	negative regulation of dendrite development

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GTP B 1230

Chain	Residue
B	ASP22
B	GLY65
B	GLY66
B	GLN67
B	ASN122
B	LYS123
B	ASP125
B	LEU126
B	CYS155
B	ALA156
B	HOH189
B	ALA23
B	HOH192
B	HOH197
B	MG1231
B	ALA24
B	GLY25
B	LYS26
B	THR27
B	THR28
B	THR41
B	THR44

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 1231

Chain	Residue
B	THR27
B	THR44
B	ASP63
B	HOH197
B	GTP1230

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16099990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19644450","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21170023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22939626","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23940353","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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