3PC3
Full length structure of cystathionine beta-synthase from Drosophila in complex with aminoacrylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004122 | molecular_function | cystathionine beta-synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006535 | biological_process | L-cysteine biosynthetic process from L-serine |
| A | 0008340 | biological_process | determination of adult lifespan |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019343 | biological_process | L-cysteine biosynthetic process via L-cystathionine |
| A | 0019344 | biological_process | L-cysteine biosynthetic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0034976 | biological_process | response to endoplasmic reticulum stress |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050421 | molecular_function | nitrite reductase (NO-forming) activity |
| A | 0050667 | biological_process | homocysteine metabolic process |
| A | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM A 701 |
| Chain | Residue |
| A | SER20 |
| A | HIS34 |
| A | ARG193 |
| A | ALA195 |
| A | PRO198 |
| A | TYR202 |
| A | ARG235 |
| A | HOH615 |
| A | HOH628 |
| A | HOH644 |
| A | HOH868 |
| A | LYS21 |
| A | HOH924 |
| A | HOH1017 |
| A | CYS22 |
| A | LYS23 |
| A | TRP24 |
| A | THR28 |
| A | GLU30 |
| A | SER32 |
| A | PRO33 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE P1T A 702 |
| Chain | Residue |
| A | LYS88 |
| A | THR115 |
| A | SER116 |
| A | GLY117 |
| A | ASN118 |
| A | THR119 |
| A | GLN191 |
| A | ALA224 |
| A | GLY225 |
| A | THR226 |
| A | ALA227 |
| A | GLY228 |
| A | THR229 |
| A | GLY274 |
| A | ILE275 |
| A | SER318 |
| A | PRO344 |
| A | ASP345 |
| A | HOH726 |
| A | HOH771 |
| A | HOH798 |
| A | HOH930 |
Functional Information from PROSITE/UniProt
| site_id | PS00901 |
| Number of Residues | 19 |
| Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KcEfln.PGgSVKdRiGyrM |
| Chain | Residue | Details |
| A | LYS77-MET95 |
