3PC2
Full length structure of cystathionine beta-synthase from Drosophila
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004122 | molecular_function | cystathionine beta-synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006535 | biological_process | cysteine biosynthetic process from serine |
| A | 0008340 | biological_process | determination of adult lifespan |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019343 | biological_process | cysteine biosynthetic process via cystathionine |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| A | 0034976 | biological_process | response to endoplasmic reticulum stress |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050421 | molecular_function | nitrite reductase (NO-forming) activity |
| A | 0050667 | biological_process | homocysteine metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM A 701 |
| Chain | Residue |
| A | SER25 |
| A | ALA200 |
| A | PRO203 |
| A | TYR207 |
| A | ARG240 |
| A | HOH688 |
| A | HOH854 |
| A | LYS26 |
| A | CYS27 |
| A | LYS28 |
| A | THR33 |
| A | GLU35 |
| A | SER37 |
| A | PRO38 |
| A | HIS39 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP A 702 |
| Chain | Residue |
| A | LYS93 |
| A | ASN123 |
| A | ALA229 |
| A | GLY230 |
| A | THR231 |
| A | ALA232 |
| A | GLY233 |
| A | THR234 |
| A | GLY279 |
| A | ILE280 |
| A | SER323 |
| A | PRO349 |
| A | ASP350 |
| A | HOH532 |
| A | HOH536 |
| A | HOH539 |
| A | HOH558 |
Functional Information from PROSITE/UniProt
| site_id | PS00901 |
| Number of Residues | 19 |
| Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KcEfln.PGgSVKdRiGyrM |
| Chain | Residue | Details |
| A | LYS82-MET100 |
