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Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3P9U

Crystal structure of TetX2 from Bacteroides thetaiotaomicron with substrate analogue

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004497	molecular_function	monooxygenase activity
A	0005737	cellular_component	cytoplasm
A	0016491	molecular_function	oxidoreductase activity
A	0046677	biological_process	response to antibiotic
A	0071949	molecular_function	FAD binding
B	0000166	molecular_function	nucleotide binding
B	0004497	molecular_function	monooxygenase activity
B	0005737	cellular_component	cytoplasm
B	0016491	molecular_function	oxidoreductase activity
B	0046677	biological_process	response to antibiotic
B	0071949	molecular_function	FAD binding
C	0000166	molecular_function	nucleotide binding
C	0004497	molecular_function	monooxygenase activity
C	0005737	cellular_component	cytoplasm
C	0016491	molecular_function	oxidoreductase activity
C	0046677	biological_process	response to antibiotic
C	0071949	molecular_function	FAD binding
D	0000166	molecular_function	nucleotide binding
D	0004497	molecular_function	monooxygenase activity
D	0005737	cellular_component	cytoplasm
D	0016491	molecular_function	oxidoreductase activity
D	0046677	biological_process	response to antibiotic
D	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	25
Details	BINDING SITE FOR RESIDUE FAD A 401

Chain	Residue
A	GLY23
A	ARG121
A	ARG137
A	LYS138
A	LEU139
A	ALA167
A	ASN168
A	GLY169
A	GLN192
A	GLY310
A	ASP311
A	GLY25
A	PRO318
A	GLN322
A	GLY323
A	VAL324
A	HOH403
A	HOH405
A	PRO26
A	VAL27
A	TYR45
A	GLU46
A	ARG47
A	LEU60
A	ARG117

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1

Chain	Residue
A	HOH8
A	GLY58
A	THR59
A	ARG213
A	ASN226

site_id	AC3
Number of Residues	23
Details	BINDING SITE FOR RESIDUE FAD B 401

Chain	Residue
B	SO41
B	ILE22
B	GLY23
B	GLY25
B	PRO26
B	VAL27
B	TYR45
B	GLU46
B	ARG47
B	LEU60
B	ARG117
B	ARG121
B	ARG137
B	LYS138
B	LEU139
B	ASN168
B	GLY169
B	GLN192
B	GLY310
B	ASP311
B	PRO318
B	GLY323
B	VAL324

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 1

Chain	Residue
B	GLY58
B	THR59
B	ARG213
B	ASN226
B	HIS234
B	FAD401

site_id	AC5
Number of Residues	22
Details	BINDING SITE FOR RESIDUE FAD C 401

Chain	Residue
C	HOH5
C	GLY23
C	GLY25
C	PRO26
C	VAL27
C	TYR45
C	GLU46
C	ARG47
C	LEU60
C	ARG117
C	ARG137
C	LYS138
C	LEU139
C	ALA167
C	ASN168
C	GLY169
C	GLN192
C	GLY310
C	ASP311
C	PRO318
C	GLY323
C	VAL324

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C 1

Chain	Residue
C	HOH5
C	GLY58
C	THR59
C	ARG213
C	PHE224
C	ASN226
C	HIS234

site_id	AC7
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FAD D 401

Chain	Residue
D	ALA167
D	ASN168
D	GLY169
D	GLN192
D	GLY310
D	ASP311
D	PRO318
D	GLN322
D	GLY323
D	VAL324
D	GLY23
D	GLY25
D	PRO26
D	VAL27
D	TYR45
D	GLU46
D	ARG47
D	LEU60
D	ARG117
D	ARG137
D	LEU139

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 1

Chain	Residue
D	HOH7
D	GLY58
D	THR59
D	ARG213
D	ALA225
D	ASN226
D	HIS234

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21590745","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XDO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A6N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GUV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00845","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00845","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"3V3O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00845","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21590745","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XDO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A6N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GUV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23999299","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2Y6Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A99","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23999299","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2Y6Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A6N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A99","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

246031

PDB entries from 2025-12-10

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