3P76
X-ray crystal structure of Aquifex aeolicus LpxC complexed SCH1379777
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006796 | biological_process | phosphate-containing compound metabolic process |
A | 0008759 | molecular_function | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity |
A | 0009245 | biological_process | lipid A biosynthetic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0019637 | biological_process | organophosphate metabolic process |
A | 0046872 | molecular_function | metal ion binding |
A | 0103117 | molecular_function | UDP-3-O-acyl-N-acetylglucosamine deacetylase activity |
A | 1901135 | biological_process | carbohydrate derivative metabolic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE IMD A 272 |
Chain | Residue |
A | PHE40 |
A | TYR45 |
A | THR88 |
A | HOH413 |
site_id | AC2 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE P76 A 273 |
Chain | Residue |
A | PHE180 |
A | ILE186 |
A | ILE189 |
A | GLY198 |
A | THR203 |
A | HIS226 |
A | LYS227 |
A | ASP230 |
A | HIS253 |
A | ZN274 |
A | ILE18 |
A | HIS58 |
A | GLU73 |
A | HIS74 |
A | THR179 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 274 |
Chain | Residue |
A | HIS74 |
A | HIS226 |
A | ASP230 |
A | P76273 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 275 |
Chain | Residue |
A | HIS58 |
A | HIS188 |
A | HOH406 |
A | HOH407 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00388, ECO:0000305|PubMed:15705580 |
Chain | Residue | Details |
A | HIS253 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00388, ECO:0000269|PubMed:12819349, ECO:0000269|PubMed:15705580, ECO:0007744|PDB:1P42, ECO:0007744|PDB:1YH8, ECO:0007744|PDB:1YHC |
Chain | Residue | Details |
A | HIS74 | |
A | HIS226 | |
A | ASP230 |