3P4G
X-ray crystal structure of a hyperactive, Ca2+-dependent, beta-helical antifreeze protein from an Antarctic bacterium
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 401 |
| Chain | Residue |
| A | ASP34 |
| A | SER36 |
| A | ASN38 |
| A | VAL52 |
| A | ALA54 |
| A | ASP57 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | MET79 |
| A | THR81 |
| A | ASP84 |
| A | LEU53 |
| A | GLY55 |
| A | ASP57 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | GLY80 |
| A | GLY82 |
| A | ASP84 |
| A | ALA98 |
| A | THR100 |
| A | ASP103 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | GLY99 |
| A | GLY101 |
| A | ASP103 |
| A | ALA117 |
| A | THR119 |
| A | ASP122 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 405 |
| Chain | Residue |
| A | GLY118 |
| A | GLY120 |
| A | ASP122 |
| A | ALA136 |
| A | THR138 |
| A | ASP141 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 406 |
| Chain | Residue |
| A | GLY137 |
| A | THR138 |
| A | ASP139 |
| A | ASP141 |
| A | ALA155 |
| A | THR157 |
| A | ASP160 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 407 |
| Chain | Residue |
| A | GLY156 |
| A | GLY158 |
| A | ASP160 |
| A | MET174 |
| A | THR176 |
| A | ASP179 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 408 |
| Chain | Residue |
| A | GLY175 |
| A | ASP177 |
| A | ASP179 |
| A | LEU195 |
| A | THR197 |
| A | ASP200 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 409 |
| Chain | Residue |
| A | ASP196 |
| A | GLY198 |
| A | ASP200 |
| A | GLY214 |
| A | THR216 |
| A | ASP219 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 410 |
| Chain | Residue |
| A | GLY215 |
| A | GLY217 |
| A | ASP219 |
| A | GLY233 |
| A | THR235 |
| A | ASP238 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 411 |
| Chain | Residue |
| A | GLY234 |
| A | GLY236 |
| A | ASP238 |
| A | LEU254 |
| A | THR256 |
| A | ASP259 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 412 |
| Chain | Residue |
| A | GLY255 |
| A | GLY257 |
| A | ASP259 |
| A | GLY273 |
| A | GLU275 |
| A | ASP278 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 413 |
| Chain | Residue |
| A | ASN274 |
| A | GLY276 |
| A | ASP278 |
| A | GLU304 |
| A | HOH1462 |
| A | HOH1615 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 324 |
| Chain | Residue |
| A | ASP139 |
| A | HOH1657 |
| A | HOH1661 |
| C | GLU104 |
| C | HOH1655 |
| C | HOH1658 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 325 |
| Chain | Residue |
| A | ASP148 |
| A | HOH1668 |
| A | HOH1669 |
| A | HOH1670 |
| A | HOH1671 |
| A | HOH1672 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 326 |
| Chain | Residue |
| A | ASP167 |
| A | HOH1551 |
| A | HOH1572 |
| A | HOH1673 |
| A | HOH1674 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 401 |
| Chain | Residue |
| B | VAL52 |
| B | ALA54 |
| B | ASP57 |
| B | ASP34 |
| B | SER36 |
| B | ASN38 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 402 |
| Chain | Residue |
| B | LEU53 |
| B | GLY55 |
| B | ASP57 |
| B | MET79 |
| B | THR81 |
| B | ASP84 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 403 |
| Chain | Residue |
| B | GLY80 |
| B | GLY82 |
| B | ASP84 |
| B | ALA98 |
| B | THR100 |
| B | ASP103 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 404 |
| Chain | Residue |
| B | GLY99 |
| B | GLY101 |
| B | ASP103 |
| B | ALA117 |
| B | THR119 |
| B | ASP122 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 405 |
| Chain | Residue |
| B | GLY118 |
| B | GLY120 |
| B | ASP122 |
| B | ALA136 |
| B | THR138 |
| B | ASP141 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 406 |
| Chain | Residue |
| B | GLY137 |
| B | ASP139 |
| B | ASP141 |
| B | ALA155 |
| B | THR157 |
| B | ASP160 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 407 |
| Chain | Residue |
| B | GLY156 |
| B | GLY158 |
| B | ASP160 |
| B | MET174 |
| B | THR176 |
| B | ASP179 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 408 |
| Chain | Residue |
| B | GLY175 |
| B | ASP177 |
| B | ASP179 |
| B | LEU195 |
| B | THR197 |
| B | ASP200 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 409 |
| Chain | Residue |
| B | ASP196 |
| B | GLY198 |
| B | ASP200 |
| B | GLY214 |
| B | THR216 |
| B | ASP219 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 410 |
| Chain | Residue |
| B | GLY215 |
| B | GLY217 |
| B | ASP219 |
| B | GLY233 |
| B | THR235 |
| B | ASP238 |
| site_id | CC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 411 |
| Chain | Residue |
| B | GLY234 |
| B | GLY236 |
| B | ASP238 |
| B | LEU254 |
| B | THR256 |
| B | ASP259 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 412 |
| Chain | Residue |
| B | GLY255 |
| B | GLY257 |
| B | ASP259 |
| B | GLY273 |
| B | GLU275 |
| B | ASP278 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 413 |
| Chain | Residue |
| B | ASN274 |
| B | GLY276 |
| B | ASP278 |
| B | GLU304 |
| B | HOH390 |
| B | HOH1618 |
| site_id | DC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 324 |
| Chain | Residue |
| B | ASP148 |
| B | HOH1663 |
| B | HOH1664 |
| B | HOH1665 |
| B | HOH1666 |
| B | HOH1667 |
| site_id | DC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 325 |
| Chain | Residue |
| A | ILE239 |
| A | VAL260 |
| A | HOH1601 |
| B | ALA54 |
| B | GLY55 |
| B | THR81 |
| B | GLY82 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 401 |
| Chain | Residue |
| C | ASP34 |
| C | SER36 |
| C | ASN38 |
| C | VAL52 |
| C | ALA54 |
| C | ASP57 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 402 |
| Chain | Residue |
| C | LEU53 |
| C | GLY55 |
| C | ASP57 |
| C | MET79 |
| C | THR81 |
| C | ASP84 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 403 |
| Chain | Residue |
| C | GLY80 |
| C | GLY82 |
| C | ASP84 |
| C | ALA98 |
| C | THR100 |
| C | ASP103 |
| site_id | DC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 404 |
| Chain | Residue |
| C | GLY99 |
| C | GLY101 |
| C | ASP103 |
| C | ALA117 |
| C | THR119 |
| C | ASP122 |
| site_id | DC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA C 405 |
| Chain | Residue |
| C | GLY118 |
| C | GLY120 |
| C | ASP122 |
| C | ALA136 |
| C | GLY137 |
| C | THR138 |
| C | ASP141 |
| site_id | EC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 406 |
| Chain | Residue |
| C | GLY137 |
| C | ASP139 |
| C | ASP141 |
| C | ALA155 |
| C | THR157 |
| C | ASP160 |
| site_id | EC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 407 |
| Chain | Residue |
| C | GLY156 |
| C | GLY158 |
| C | ASP160 |
| C | MET174 |
| C | THR176 |
| C | ASP179 |
| site_id | EC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 408 |
| Chain | Residue |
| C | GLY175 |
| C | ASP177 |
| C | ASP179 |
| C | LEU195 |
| C | THR197 |
| C | ASP200 |
| site_id | EC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 409 |
| Chain | Residue |
| C | ASP196 |
| C | GLY198 |
| C | ASP200 |
| C | GLY214 |
| C | THR216 |
| C | ASP219 |
| site_id | EC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 410 |
| Chain | Residue |
| C | GLY215 |
| C | GLY217 |
| C | ASP219 |
| C | GLY233 |
| C | THR235 |
| C | ASP238 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 411 |
| Chain | Residue |
| C | GLY234 |
| C | GLY236 |
| C | ASP238 |
| C | LEU254 |
| C | THR256 |
| C | ASP259 |
| site_id | EC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 412 |
| Chain | Residue |
| C | GLY255 |
| C | GLY257 |
| C | ASP259 |
| C | GLY273 |
| C | GLU275 |
| C | ASP278 |
| site_id | EC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 413 |
| Chain | Residue |
| C | ASN274 |
| C | GLY276 |
| C | ASP278 |
| C | GLU304 |
| C | HOH390 |
| C | HOH431 |
| site_id | EC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT C 324 |
| Chain | Residue |
| C | THR235 |
| C | GLY236 |
| C | THR256 |
| C | GLY257 |
| C | HOH1519 |
| D | SER36 |
| D | ASN37 |
| site_id | FC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 401 |
| Chain | Residue |
| D | ASP34 |
| D | SER36 |
| D | ASN38 |
| D | VAL52 |
| D | ALA54 |
| D | ASP57 |
| site_id | FC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 402 |
| Chain | Residue |
| D | LEU53 |
| D | GLY55 |
| D | ASP57 |
| D | MET79 |
| D | THR81 |
| D | ASP84 |
| site_id | FC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 403 |
| Chain | Residue |
| D | GLY80 |
| D | GLY82 |
| D | ASP84 |
| D | ALA98 |
| D | THR100 |
| D | ASP103 |
| site_id | FC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 404 |
| Chain | Residue |
| D | GLY99 |
| D | GLY101 |
| D | ASP103 |
| D | ALA117 |
| D | THR119 |
| D | ASP122 |
| site_id | FC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 405 |
| Chain | Residue |
| D | GLY118 |
| D | GLY120 |
| D | ASP122 |
| D | ALA136 |
| D | THR138 |
| D | ASP141 |
| site_id | FC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA D 406 |
| Chain | Residue |
| D | GLY137 |
| D | THR138 |
| D | ASP139 |
| D | ASP141 |
| D | ALA155 |
| D | THR157 |
| D | ASP160 |
| site_id | FC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 407 |
| Chain | Residue |
| D | GLY156 |
| D | GLY158 |
| D | ASP160 |
| D | MET174 |
| D | THR176 |
| D | ASP179 |
| site_id | FC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 408 |
| Chain | Residue |
| D | GLY175 |
| D | ASP177 |
| D | ASP179 |
| D | LEU195 |
| D | THR197 |
| D | ASP200 |
| site_id | FC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 409 |
| Chain | Residue |
| D | ASP196 |
| D | GLY198 |
| D | ASP200 |
| D | GLY214 |
| D | THR216 |
| D | ASP219 |
| site_id | GC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 410 |
| Chain | Residue |
| D | GLY215 |
| D | GLY217 |
| D | ASP219 |
| D | GLY233 |
| D | THR235 |
| D | ASP238 |
| site_id | GC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 411 |
| Chain | Residue |
| D | GLY234 |
| D | GLY236 |
| D | ASP238 |
| D | LEU254 |
| D | THR256 |
| D | ASP259 |
| site_id | GC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 412 |
| Chain | Residue |
| D | GLY255 |
| D | GLY257 |
| D | ASP259 |
| D | GLY273 |
| D | GLU275 |
| D | ASP278 |
| site_id | GC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 413 |
| Chain | Residue |
| D | ASN274 |
| D | GLY276 |
| D | ASP278 |
| D | GLU304 |
| D | HOH702 |
| D | HOH1625 |
