3P4E
Phosphoribosylformylglycinamidine cyclo-ligase from Vibrio cholerae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004637 | molecular_function | phosphoribosylamine-glycine ligase activity |
| A | 0004641 | molecular_function | phosphoribosylformylglycinamidine cyclo-ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046084 | biological_process | adenine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE AMP A 501 |
| Chain | Residue |
| A | VAL24 |
| A | HOH607 |
| A | HOH608 |
| A | HOH609 |
| A | HOH610 |
| A | ASP108 |
| A | ILE124 |
| A | GLY140 |
| A | GLY141 |
| A | GLU142 |
| A | THR143 |
| A | HOH523 |
| A | HOH606 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 502 |
| Chain | Residue |
| A | LYS80 |
| A | ASP82 |
| A | LEU213 |
| A | TRP282 |
| A | GLU285 |
| A | HOH432 |
| A | HOH497 |
| A | HOH624 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CIT A 503 |
| Chain | Residue |
| A | ASN193 |
| A | GLY194 |
| A | TYR195 |
| A | SER196 |
| A | LEU197 |
| A | GLY250 |
| A | HOH360 |
| A | HOH535 |
| A | HOH536 |
| A | HOH599 |
| A | HOH600 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 504 |
| Chain | Residue |
| A | VAL98 |
| A | ILE171 |
| A | ALA244 |
| A | ILE245 |
