3P4E
Phosphoribosylformylglycinamidine cyclo-ligase from Vibrio cholerae
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004637 | molecular_function | phosphoribosylamine-glycine ligase activity |
A | 0004641 | molecular_function | phosphoribosylformylglycinamidine cyclo-ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006164 | biological_process | purine nucleotide biosynthetic process |
A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
A | 0016874 | molecular_function | ligase activity |
A | 0046084 | biological_process | adenine biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE AMP A 501 |
Chain | Residue |
A | VAL24 |
A | HOH607 |
A | HOH608 |
A | HOH609 |
A | HOH610 |
A | ASP108 |
A | ILE124 |
A | GLY140 |
A | GLY141 |
A | GLU142 |
A | THR143 |
A | HOH523 |
A | HOH606 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 502 |
Chain | Residue |
A | LYS80 |
A | ASP82 |
A | LEU213 |
A | TRP282 |
A | GLU285 |
A | HOH432 |
A | HOH497 |
A | HOH624 |
site_id | AC3 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE CIT A 503 |
Chain | Residue |
A | ASN193 |
A | GLY194 |
A | TYR195 |
A | SER196 |
A | LEU197 |
A | GLY250 |
A | HOH360 |
A | HOH535 |
A | HOH536 |
A | HOH599 |
A | HOH600 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 504 |
Chain | Residue |
A | VAL98 |
A | ILE171 |
A | ALA244 |
A | ILE245 |