3OZ2

Crystal structure of a geranylgeranyl bacteriochlorophyll reductase-like (Ta0516) from Thermoplasma acidophilum at 1.60 A resolution

Replaces:  3CGV

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0006650	biological_process	glycerophospholipid metabolic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016628	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
A	0045550	molecular_function	geranylgeranyl reductase activity
A	0046467	biological_process	membrane lipid biosynthetic process
A	0046474	biological_process	glycerophospholipid biosynthetic process
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	37
Details	BINDING SITE FOR RESIDUE FAD A 501

Chain	Residue
A	GLY10
A	GLY45
A	GLU46
A	GLY47
A	ARG100
A	PRO123
A	ALA124
A	ALA156
A	ASP157
A	GLY158
A	GLU162
A	GLY12
A	PHE213
A	VAL264
A	GLY282
A	ASP283
A	GLY294
A	GLY295
A	ILE296
A	ALA299
A	OZ2502
A	HOH517
A	PRO13
A	HOH518
A	HOH524
A	HOH528
A	HOH622
A	HOH623
A	HOH628
A	HOH630
A	HOH687
A	GLY14
A	GLU33
A	LYS34
A	ARG35
A	ARG43
A	CYS44

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE OZ2 A 502

Chain	Residue
A	SER49
A	TYR209
A	TRP211
A	PRO290
A	ILE291
A	THR292
A	GLY293
A	LYS338
A	LEU349
A	ILE372
A	SER373
A	VAL374
A	FAD501
A	EDO508
A	GOL515
A	HOH655
A	HOH805
A	HOH836

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 503

Chain	Residue
A	VAL118
A	TRP119
A	VAL120
A	HIS141
A	HOH575
A	HOH790

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 504

Chain	Residue
A	LYS138
A	GLU312
A	GLU315
A	HOH616

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 505

Chain	Residue
A	GLY132
A	LYS133
A	VAL134
A	MSE275
A	HOH585

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 506

Chain	Residue
A	TYR4
A	HOH670
A	HOH747

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 507

Chain	Residue
A	ASN177
A	SER227
A	LYS346
A	GLU347
A	HOH617
A	HOH785

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 508

Chain	Residue
A	ASP289
A	THR292
A	GLY294
A	ASN298
A	OZ2502
A	EDO509

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 509

Chain	Residue
A	ASN298
A	VAL301
A	ARG334
A	LYS338
A	EDO508
A	HOH666

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 510

Chain	Residue
A	ASP117
A	TRP119
A	HOH635

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 511

Chain	Residue
A	HOH558
A	HOH684
A	HOH769
A	HOH788

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 512

Chain	Residue
A	LEU27
A	HOH557
A	HOH633
A	HOH705
A	ALA23

---

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 513

Chain	Residue
A	GLY254
A	LYS270
A	MSE271
A	HOH589
A	HOH626
A	HOH672
A	HOH765

---

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 514

Chain	Residue
A	PRO272
A	THR274
A	MSE275
A	PRO321
A	MSE324
A	GLN325
A	GLU328
A	HOH604

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 515

Chain	Residue
A	GLY47
A	LEU48
A	SER49
A	VAL69
A	THR197
A	OZ2502

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20869368","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3OZ2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20869368","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3OZ2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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